Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

7.7%

1 terminated/withdrawn out of 13 trials

Success Rate

90.9%

+4.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

5 of 10 completed trials have results

Key Signals

5 with results

Enrollment Performance

Analytics

Phase 1
7(58.3%)
Phase 2
5(41.7%)
12Total
Phase 1(7)
Phase 2(5)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT05225415Phase 2Completed

Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies

Role: lead

NCT06961760Unknown

Expanded Access Program for CT1812 (Zervimesine)

Role: lead

NCT05531656Phase 2Active Not Recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

Role: lead

NCT03507790Phase 2Completed

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Role: lead

NCT05893537Phase 2Terminated

Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

Role: lead

NCT04735536Phase 2Completed

Pilot Clinical Study of CT1812 in Mild to Moderate Alzheimer's Disease Using EEG

Role: lead

NCT03493282Phase 1Completed

Effect of CT1812 Treatment on Brain Synaptic Density

Role: lead

NCT05225389Phase 1Completed

Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of CT1812 in Healthy Adult Male Subjects

Role: lead

NCT05248672Phase 1Completed

Study to Assess the Pharmacokinetics of CT1812 in Older Healthy Volunteers

Role: lead

NCT03522129Phase 1Completed

Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease

Role: lead

NCT03716427Phase 1Completed

Drug Interaction Study of CT1812 in Healthy Volunteers

Role: lead

NCT02907567Phase 1Completed

Clinical Trial of CT1812 in Mild to Moderate Alzheimer's Disease

Role: lead

NCT02570997Phase 1Completed

Ascending Dose Study of CT1812 in Healthy Volunteers

Role: lead

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