Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

35.7%

15 terminated/withdrawn out of 42 trials

Success Rate

54.5%

-32.0% vs industry average

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

117%

21 of 18 completed trials have results

Key Signals

1 recruiting21 with results12 terminated

Enrollment Performance

Analytics

Phase 2
23(57.5%)
Phase 1
15(37.5%)
Phase 3
2(5.0%)
40Total
Phase 2(23)
Phase 1(15)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (42)

Showing 20 of 42 trials
NCT03694262Phase 2Completed

The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)

Role: collaborator

NCT02873962Phase 2Active Not Recruiting

A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib

Role: collaborator

NCT03899155Phase 2Recruiting

Pan Tumor Rollover Study

Role: collaborator

NCT03617679Phase 2Completed

Rucaparib vs Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer

Role: collaborator

NCT04539327Completed

Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study

Role: collaborator

NCT03559049Phase 1Terminated

Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer

Role: collaborator

NCT03338790Phase 2Completed

An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Role: collaborator

NCT03542175Phase 1Completed

A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy

Role: collaborator

NCT04624178Phase 2Active Not Recruiting

A Study of Rucaparib and Nivolumab in People With Leiomyosarcoma

Role: collaborator

NCT02678182Phase 2Active Not Recruiting

Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial

Role: collaborator

NCT04253262Phase 1Active Not Recruiting

A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

Role: collaborator

NCT05180162Phase 1Completed

Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286

Role: collaborator

NCT03552471Phase 1Completed

Mirvetuximab Soravtansine and Rucaparib Camsylate in Treating Participants With Recurrent Endometrial, Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Role: collaborator

NCT04227522Phase 3Completed

Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients

Role: collaborator

NCT03958045Phase 2Completed

Combination Rucaparib With Nivolumab in Small Cell Lung Carcinoma

Role: collaborator

NCT03413995Phase 2Completed

Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations

Role: collaborator

NCT01074970Phase 2Completed

PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

Role: collaborator

NCT03533946Phase 2Terminated

Rucaparib in Nonmetastatic prOstAte With BRCAness

Role: collaborator

NCT03476798Phase 2Completed

Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium

Role: collaborator

NCT04151563Phase 1Withdrawn

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy

Role: collaborator