Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

0.0%

0 terminated/withdrawn out of 17 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

29%

5 trials in Phase 3/4

Results Transparency

69%

11 of 16 completed trials have results

Key Signals

11 with results

Enrollment Performance

Analytics

Phase 2
9(56.3%)
Phase 3
5(31.3%)
Phase 1
2(12.5%)
16Total
Phase 2(9)
Phase 3(5)
Phase 1(2)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT05854784Phase 2Completed

Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Variegate Porphyria (VP)

Role: lead

NCT04525157Phase 2Completed

Afamelanotide and Narrow-Band Ultraviolet B (NB-UVB) Phototherapy in the Treatment of Nonsegmental Vitiligo (NSV)

Role: lead

NCT04962503Phase 2Completed

A Proof of Concept Study to Evaluate the Safety of Afamelanotide in Patients With Acute Arterial Ischaemic Stroke (AIS)

Role: lead

NCT04943159Phase 2Completed

Afamelanotide in Patients Suffering With Acne Vulgaris

Role: lead

NCT00979745Phase 3Completed

Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP)

Role: lead

NCT04425746Phase 2Completed

Afamelanotide as Adjunctive Therapy in Patients Undergoing Photodynamic Therapy (PDT) Utilising Porfimer Sodium

Role: lead

NCT04704713Phase 3Completed

Afamelanotide in Patients Suffering From Polymorphic Light Eruption (PLE)

Role: lead

NCT04578496Phase 3Completed

A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP)

Role: lead

NCT01097044Phase 2Completed

Phase II Confirmatory Study in Erythropoietic Protoporphyria (EPP)

Role: lead

NCT04053270Phase 3Completed

Multicentre Phase III Erythropoietic Protoporphyria Study

Role: lead

NCT01605136Phase 3Completed

Phase III Confirmatory Study in Erythropoietic Protoporphyria

Role: lead

NCT03634137Phase 1Completed

Implant Pharmacokinetic and Pharmacodynamic Study

Role: lead

NCT01382589Phase 2Completed

Afamelanotide and Narrow-Band Ultraviolet B (NB-UVB) Light in the Treatment of Nonsegmental Vitiligo

Role: lead

NCT01430195Phase 1Completed

Afamelanotide and Narrow-Band Ultraviolet B (NB-UVB) Light in the Treatment of Nonsegmental Vitiligo (NSV)

Role: lead

NCT00472901Completed

Phase III Trial of CUV1647 in Polymorphic Light Eruption (PLE)

Role: lead

NCT00829192Phase 2Unknown

Phase II AK Study in Organ Transplant Patients

Role: lead

NCT00859534Phase 2Completed

Phase II Solar Urticaria (SU) Pilot Study

Role: lead

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