Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 30/100

Failure Rate

14.3%

2 terminated/withdrawn out of 14 trials

Success Rate

85.7%

-0.8% vs industry average

Late-Stage Pipeline

29%

4 trials in Phase 3/4

Results Transparency

100%

12 of 12 completed trials have results

Key Signals

12 with results

Enrollment Performance

Analytics

Phase 3
4(36.4%)
Phase 2
4(36.4%)
Phase 1
3(27.3%)
11Total
Phase 3(4)
Phase 2(4)
Phase 1(3)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT05891548Phase 2Completed

Study to Evaluate Suprachoroidally Administered CLS-AX in the Treatment of Neovascular Age-Related Macular Degeneration

Role: lead

NCT05131646Completed

Extension Study to Evaluate the Long-term Outcomes of Subjects in the CLS-AX CLS1002-101 Study

Role: lead

NCT04626128Phase 1Completed

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD

Role: lead

NCT03097315Phase 3Completed

Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis

Role: lead

NCT02952001Completed

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

Role: lead

NCT02595398Phase 3Completed

Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis

Role: lead

NCT02949024Phase 1Completed

Suprachoroidal Injection of CLS-TA Alone or With Aflibercept in Subjects With Diabetic Macular Edema

Role: lead

NCT03126786Phase 2Completed

Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema

Role: lead

NCT03203447Phase 3Terminated

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO

Role: lead

NCT02980874Phase 3Terminated

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO

Role: lead

NCT01789320Phase 1Completed

Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis

Role: lead

NCT02255032Phase 2Completed

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis

Role: lead

NCT02303184Phase 2Completed

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO

Role: lead

NCT02956330Completed

Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201

Role: lead

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