Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

7.1%

8 terminated/withdrawn out of 112 trials

Success Rate

90.2%

+3.7% vs industry average

Late-Stage Pipeline

51%

57 trials in Phase 3/4

Results Transparency

23%

17 of 74 completed trials have results

Key Signals

12 recruiting17 with results8 terminated

Enrollment Performance

Analytics

Phase 3
55(55.6%)
Phase 1
25(25.3%)
Phase 2
14(14.1%)
N/A
3(3.0%)
Phase 4
2(2.0%)
99Total
Phase 3(55)
Phase 1(25)
Phase 2(14)
N/A(3)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (112)

Showing 20 of 112 trials
NCT06793215Phase 3Recruiting

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Role: collaborator

NCT05271409Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Role: collaborator

NCT06819891Phase 3Recruiting

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Role: collaborator

NCT07416604Phase 3Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

Role: collaborator

NCT05503264Phase 3Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Satralizumab in Participants With Anti-N-methyl-D-aspartic Acid Receptor (NMDAR) or Anti-leucine-rich Glioma-inactivated 1 (LGI1) Encephalitis

Role: collaborator

NCT07416526Phase 3Recruiting

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

Role: collaborator

NCT06819878Phase 3Recruiting

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Role: collaborator

NCT07617337Phase 1Not Yet Recruiting

AQUA07 in Patients With ALK-Positive Non-Small Cell Lung Cancer

Role: lead

NCT07239336Phase 2Recruiting

Study of DONQ52 in Active Celiac Disease

Role: lead

NCT03157635Phase 1Active Not Recruiting

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria

Role: collaborator

NCT04434092Phase 3Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

Role: collaborator

NCT04432584Phase 3Active Not Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

Role: collaborator

NCT05867121Phase 1Active Not Recruiting

A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors; Urothelial Carcinoma Substudy in Association With RO7496353 Study GO44010

Role: collaborator

NCT04861259Phase 3Active Not Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Role: collaborator

NCT04732598Phase 3Completed

A Phase III Study of Bevacizumab and Paclitaxel in Combination With Atezolizumab as a Treatment for Locally Advanced Unresectable or Metastatic Hormone Receptor-positive HER2 Negative Breast Cancer

Role: collaborator

NCT06497556Phase 3Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer

Role: collaborator

NCT06723106Phase 1Enrolling By Invitation

Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)

Role: lead

NCT06371417Phase 1Recruiting

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Role: lead

NCT04958265Phase 3Active Not Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Role: collaborator

NCT04338269Phase 3Terminated

A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment

Role: collaborator