Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

0.0%

0 terminated/withdrawn out of 17 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

24%

4 trials in Phase 3/4

Results Transparency

0%

0 of 11 completed trials have results

Key Signals

2 recruiting

Enrollment Performance

Analytics

Phase 1
9(52.9%)
Phase 2
4(23.5%)
Phase 3
4(23.5%)
17Total
Phase 1(9)
Phase 2(4)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (17)

Showing 17 of 17 trials
NCT07551167Phase 1Not Yet Recruiting

A Clinical Study of HRS-5765 in Healthy Participants

Role: lead

NCT06674915Phase 1Completed

Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HRS-5965 in Subjects With Hepatic Impairment

Role: lead

NCT06715943Phase 3Completed

Efficacy and Safety of HRS-5965 in Patients With PNH Who Are Still Anemia After Anti-C5 Antibody Treatment

Role: lead

NCT06238544Phase 2Active Not Recruiting

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Role: lead

NCT06490991Phase 1Completed

Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects

Role: lead

NCT07230418Phase 1Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Doses of HRS-3095 Oral Administration in Healthy Subjects, as Well as the Effect of HRS-3095 on CYP3A4 Metabolic Enzymes

Role: lead

NCT06593938Phase 3Completed

A Study to Evaluate the Efficacy and Safety of Oral HRS-5965 in Adult Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

Role: lead

NCT07040787Phase 1Completed

Investigation of Drug-drug Interaction of HRS-5965 With Clopidogrel and Clarithromycin in Healthy Subjects

Role: lead

NCT07035665Phase 1Completed

A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects

Role: lead

NCT07014826Phase 3Recruiting

A Trial of HRS-5965 Capsule in Primary IgA Nephropathy

Role: lead

NCT06684041Phase 1Completed

A Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Study, and QT Interval Study of HRS-5965 Capsules in Healthy Subjects

Role: lead

NCT06137768Phase 2Active Not Recruiting

A Trial of HRS-5965 Tablets in Primary IgA Nephropathy

Role: lead

NCT05905458Phase 2Completed

A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs)

Role: lead

NCT05505955Phase 1Completed

Study of HRS-5965 in Healthy Subjects and Subjects With Renal Insufficiency

Role: lead

NCT06567392Phase 1Completed

A Study to Evaluate the Mass Balance of [14C] HRS-5965 in Healthy Adult Male Volunteers

Role: lead

NCT06051357Phase 2Completed

Proof of Concept Study to Assess the Efficacy, Safety of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Role: lead

NCT04994080Phase 3Unknown

A Study to Assess the Efficacy and Safety of Paricalcitol in the Treatment of Chronic Kidney Disease With Secondary Hyperparathyroidism

Role: lead

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