Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

15.4%

2 terminated/withdrawn out of 13 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

15%

2 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed trials have results

Key Signals

3 recruiting

Enrollment Performance

Analytics

Phase 1
10(76.9%)
Phase 3
2(15.4%)
Phase 2
1(7.7%)
13Total
Phase 1(10)
Phase 3(2)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT03370198Phase 1Terminated

Hepatic Transarterial Administrations of NKR-2 in Patients With Unresectable Liver Metastases From Colorectal Cancer

Role: lead

NCT04613557Phase 1Active Not Recruiting

Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT04991948Phase 1Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

Role: lead

NCT03466320Phase 1Completed

DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2

Role: lead

NCT03692429Phase 1Recruiting

alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells

Role: lead

NCT03310008Phase 1Unknown

Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases

Role: lead

NCT04167696Phase 1Recruiting

Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02

Role: lead

NCT03612739Phase 1Withdrawn

EPITHINK: Epigenetic Drug Treatment and Therapeutic Immunotherapy With NKR-2

Role: lead

NCT03018405Phase 1Unknown

A Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Cancer Indications

Role: lead

NCT02203825Phase 1Completed

Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands

Role: lead

NCT01768702Phase 3Completed

Safety and Efficacy of Autologous Cardiopoietic Cells for Treatment of Ischemic Heart Failure.

Role: lead

NCT02317458Phase 3Unknown

Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-2) Trial - THE CHART-2 TRIAL

Role: lead

NCT00810238Phase 2Completed

C-Cure Clinical Trial

Role: lead

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