Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

31.6%

6 terminated/withdrawn out of 19 trials

Success Rate

45.5%

-41.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

60%

3 of 5 completed trials have results

Key Signals

4 recruiting3 with results

Enrollment Performance

Analytics

Phase 2
9(47.4%)
Phase 1
7(36.8%)
Early Phase 1
3(15.8%)
19Total
Phase 2(9)
Phase 1(7)
Early Phase 1(3)

Activity Timeline

Global Presence

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Clinical Trials (19)

Showing 19 of 19 trials
NCT04260256Phase 2Terminated

A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors

Role: lead

NCT03367962Phase 1Completed

Detection of Graft Versus Host Disease With [18F]F-AraG

Role: lead

NCT07168785Early Phase 1Not Yet Recruiting

[18F]-AraG PET Imaging in LA HNSCC

Role: collaborator

NCT04678440Early Phase 1Completed

[18F]F-AraG/Total Body PET Imaging and Healthy Subjects and Lung Cancer Patients

Role: collaborator

NCT05096234Phase 1Terminated

18F-F-AraG PET Imaging to Evaluate Immunological Response to CAR T Cell Therapy in Lymphoma

Role: collaborator

NCT04815096Phase 2Recruiting

Imaging Immune Activation in COVID-19

Role: lead

NCT06107374Phase 2Recruiting

Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

Role: lead

NCT06084806Phase 2Recruiting

Test-retest Evaluation of [18F]F-AraG PET

Role: lead

NCT03684655Phase 2Recruiting

Imaging Immune Activation in HIV by PET-MR

Role: lead

NCT04401995Phase 2Completed

Study of TLR9 Agonist Vidutolimod (CMP-001) in Combination with Nivolumab Vs. Nivolumab

Role: collaborator

NCT04524195Phase 1Terminated

PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)

Role: collaborator

NCT04726215Phase 2Unknown

Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer

Role: lead

NCT03129061Phase 1Completed

Study to Evaluate Immunological Response to PD-1 Inhibition in Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Role: lead

NCT03142204Phase 1Unknown

[18F]FAraG PET Imaging for Analysis of Biodistribution in Cancer Patients Expected to Undergo Immunotherapy and/or Radiation Therapy

Role: lead

NCT04052412Phase 1Unknown

Biodistribution and Kinetics of 18F-AraG in Non-Small Cell Lung Cancer

Role: collaborator

NCT04186988Early Phase 1Withdrawn

[18F]-AraG for the Detection of T-Cell Activation in Advanced Non-small Cell Lung Cancer Patients Undergoing PD-1/PD-L1-Directed Therapy

Role: collaborator

NCT03007719Phase 2Terminated

Functional Imaging of T-Cell Activation With [18F]F-AraG in Urothelial Carcinoma Patients Receiving Neoadjuvant Therapy or Patients With Cancer Receiving Standard of Care Anti-PD-1/L1

Role: collaborator

NCT03311672Phase 2Withdrawn

T-Cell PET Imaging With [18F]F-AraG in Lung Cancer

Role: collaborator

NCT02323893Phase 1Completed

Study of Kinetics, Dosimetry & Safety of [18F]F-AraG, a Positron Emission Tomography Imaging Tracer in Healthy Humans

Role: lead

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