Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

25.0%

4 terminated/withdrawn out of 16 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

6%

1 trials in Phase 3/4

Results Transparency

25%

2 of 8 completed trials have results

Key Signals

1 recruiting2 with results

Enrollment Performance

Analytics

Phase 1
8(53.3%)
Phase 2
6(40.0%)
Phase 3
1(6.7%)
15Total
Phase 1(8)
Phase 2(6)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (16)

Showing 16 of 16 trials
NCT07311993Phase 1Recruiting

Phase 1 Study of CLR 125 in Triple Negative Breast Cancer

Role: lead

NCT02952508Phase 2Active Not Recruiting

Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom

Role: lead

NCT03478462Phase 1Active Not Recruiting

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

Role: lead

NCT05610891Phase 1Active Not Recruiting

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

Role: lead

NCT04105543Phase 1Completed

CLR 131 Combined With Radiation for Head and Neck Cancer

Role: collaborator

NCT02278315Phase 1Completed

Dose Escalation Study of I-131-CLR1404 in Patients With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT00347412Phase 3Completed

Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer

Role: lead

NCT01058512Phase 2Completed

A Trial of NOV-205 in Hepatitis C Patients Who Failed Standard Therapy

Role: lead

NCT01662284Terminated

Study of 124I-NM404 in Advanced Solid Malignancies

Role: collaborator

NCT00582283Phase 1Completed

NM404 as an Imaging Agent in Patients With NSCLC

Role: collaborator

NCT01898273Phase 2Terminated

Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma

Role: lead

NCT00345540Phase 2Completed

Efficacy of NOV-002 in Combination With Carboplatin in Chemotherapy-resistant Ovarian Cancer

Role: lead

NCT01495663Phase 1Completed

Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned

Role: lead

NCT01778088Phase 2Withdrawn

Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma

Role: lead

NCT00960726Phase 2Withdrawn

NOV-002 in Myelodysplastic Syndrome (MDS)

Role: collaborator

NCT00372983Phase 1Completed

Safety and PK Study of NOV-205 to Treat Chronic HCV Who Fail Standard Therapy

Role: lead

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