Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

14.3%

2 terminated/withdrawn out of 14 trials

Success Rate

85.7%

-0.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

17%

2 of 12 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 1
12(85.7%)
Phase 2
2(14.3%)
14Total
Phase 1(12)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (14)

Showing 14 of 14 trials
NCT03054363Phase 1Completed

Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

Role: collaborator

NCT01259869Phase 2Completed

A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression

Role: collaborator

NCT03758339Phase 1Completed

A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants

Role: lead

NCT01408316Phase 1Completed

Study of the Pharmacokinetics and Pharmacodynamics of Crystalline PX-866 Tablets and Amorphous PX-866 Capsules in Healthy Volunteers

Role: lead

NCT00726583Phase 1Completed

Phase I Trial of Oral PX-866

Role: lead

NCT02270372Phase 1Completed

Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer

Role: lead

NCT01978964Phase 1Completed

Phase 1b Maintenance Therapy Study of ONT-10 in Patients With Solid Tumors

Role: lead

NCT00522652Phase 1Completed

Phase I Trial of PX-478

Role: lead

NCT01556789Phase 1Completed

Phase 1 Study of ONT-10 in Patients With Solid Tumors

Role: lead

NCT00736372Phase 1Completed

A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer

Role: lead

NCT01252628Phase 1Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Role: lead

NCT01616199Phase 1Terminated

Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma

Role: lead

NCT01204099Phase 1Completed

Study of PX-866 and Docetaxel in Solid Tumors

Role: lead

NCT00417287Phase 2Terminated

Phase II Study of PX-12 in Patients With Advanced Pancreatic Cancer

Role: lead

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