Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

20.7%

18 terminated/withdrawn out of 87 trials

Success Rate

70.0%

-16.5% vs industry average

Late-Stage Pipeline

16%

14 trials in Phase 3/4

Results Transparency

2%

1 of 42 completed trials have results

Key Signals

10 recruiting1 with results17 terminated

Enrollment Performance

Analytics

Phase 2
25(40.3%)
Phase 3
14(22.6%)
Phase 1
12(19.4%)
N/A
11(17.7%)
62Total
Phase 2(25)
Phase 3(14)
Phase 1(12)
N/A(11)

Activity Timeline

Global Presence

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Clinical Trials (87)

Showing 20 of 87 trials
NCT04136353Phase 3Active Not Recruiting

Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate

Role: collaborator

NCT02446444Phase 3Active Not Recruiting

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer

Role: collaborator

NCT07552168Phase 2Recruiting

INSPIRE: INnovative SABR for Prostate Cancer All IREland

Role: lead

NCT04608318Phase 3Active Not Recruiting

Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)

Role: collaborator

NCT03862911Not ApplicableActive Not Recruiting

Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer

Role: collaborator

NCT04595565Phase 3Active Not Recruiting

Sacituzumab Govitecan in Primary HER2-negative Breast Cancer

Role: collaborator

NCT00951535Phase 2Active Not Recruiting

A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0 M0 Prostate Cancer. ICORG 08-17

Role: lead

NCT03843346Completed

The Impact of the Gene Recurrence Score on Chemotherapy Prescribing in ER Positive, Lymph Node Positive Early Stage Breast Cancer

Role: lead

NCT05518110Phase 2Terminated

PaTcH Study: A Phase 2 Study of Trametinib and Hydroxychloroquine in Patients With Metastatic Refractory Pancreatic Cancer

Role: lead

NCT02764086Phase 1Terminated

INTENSE: A Phase I/II Study of INhomogeneous Targeted Dose Escalation in Non-Small CEll Lung Cancer

Role: lead

NCT02705859Phase 1Completed

Phase Ib/II Trial of coPANlisib in Combination With Trastuzumab in HER2-positive Breast Cancer. (Panther Study)

Role: lead

NCT06274541Completed

Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study

Role: lead

NCT03869762Phase 2Terminated

Denosumab in Combination With Enzalutamide in Progressive Metastatic Castrate-resistant Prostate Cancer and Bone Metastases.

Role: lead

NCT02151019Phase 1Terminated

Pre-operative 3-DCRT vs IMRT for Locally Advanced Rectal Cancer

Role: lead

NCT04667663Phase 1Active Not Recruiting

CPD-DARA in Patients With Relapsed/Refractory Multiple Myeloma.

Role: lead

NCT01822444Completed

ANGIOPREDICT. ICORG 12-16, V3

Role: lead

NCT02160353Phase 2Completed

Neo-adjuvant Abiraterone Prostate Study

Role: lead

NCT02225704Phase 2Completed

Radium-223 in Combination With Enzalutamide

Role: lead

NCT01164150Phase 2Terminated

Prospective Randomised Phase II Trial Evaluating Adjuvant Pelvic Radiotherapy Using Either IMRT or 3-Dimensional Planning for Endometrial Cancer. ICORG 09-06

Role: lead

NCT03699111Completed

Identification of New Patient Stratification Tools in MSS RAS mt mCRC

Role: lead