Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

9.1%

1 terminated/withdrawn out of 11 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed trials have results

Key Signals

2 with results

Enrollment Performance

Analytics

Phase 1
9(81.8%)
Phase 3
1(9.1%)
Phase 2
1(9.1%)
11Total
Phase 1(9)
Phase 3(1)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT06359002Phase 1Active Not Recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.

Role: lead

NCT06932952Phase 1Active Not Recruiting

A Dose Escalation and Expansion Trial With BYON4228 Alone and in Combination in Patients With Advanced or Metastatic Solid Tumors

Role: lead

NCT05737628Phase 1Active Not Recruiting

First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228

Role: lead

NCT05323045Phase 1Completed

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

Role: lead

NCT04205630Phase 2Completed

SYD985 in Patients With HER2-expressing Recurrent, Advanced or Metastatic Endometrial Carcinoma

Role: lead

NCT04983238Phase 1Completed

Evaluation of Safety and Efficacy of Sodium Thiosulfate (BYON5667) Eye Drops to Reduce Ocular Toxicity in Cancer Patients Treated With SYD985

Role: lead

NCT04235101Phase 1Completed

Phase I Study of SYD985 With Niraparib in Patients With Solid Tumors

Role: lead

NCT04602117Phase 1Withdrawn

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Role: collaborator

NCT03262935Phase 3Completed

SYD985 vs. Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer

Role: lead

NCT02277717Phase 1Completed

First-in-human Study With the Antibody-drug Conjugate SYD985 to Evaluate Safety and Efficacy in Cancer Patients

Role: lead

NCT04202705Phase 1Completed

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate SYD1875

Role: lead

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