Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

17.6%

6 terminated/withdrawn out of 34 trials

Success Rate

75.0%

-11.5% vs industry average

Late-Stage Pipeline

53%

18 trials in Phase 3/4

Results Transparency

106%

19 of 18 completed trials have results

Key Signals

2 recruiting19 with results6 terminated

Enrollment Performance

Analytics

Phase 3
18(54.5%)
Phase 2
8(24.2%)
N/A
6(18.2%)
Phase 1
1(3.0%)
33Total
Phase 3(18)
Phase 2(8)
N/A(6)
Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (34)

Showing 20 of 34 trials
NCT02032823Phase 3Active Not Recruiting

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer

Role: collaborator

NCT02513394Phase 3Active Not Recruiting

PALbociclib CoLlaborative Adjuvant Study

Role: collaborator

NCT02308085Not ApplicableActive Not Recruiting

Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer

Role: collaborator

NCT00066703Phase 3Completed

Triptorelin With Either Exemestane or Tamoxifen in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Role: collaborator

NCT00066690Phase 3Completed

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Role: collaborator

NCT01358877Phase 3Completed

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

Role: collaborator

NCT02889874Not ApplicableActive Not Recruiting

EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer

Role: collaborator

NCT05128773Phase 3Terminated

Study of Amcenestrant (SAR439859) Versus Tamoxifen for Patients With Hormone Receptor-positive (HR+) Early Breast Cancer, Who Have Discontinued Adjuvant Aromatase Inhibitor Therapy Due to Treatment-related Toxicity

Role: collaborator

NCT05063786Phase 3Active Not Recruiting

Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET)

Role: collaborator

NCT05512364Phase 3Recruiting

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)

Role: collaborator

NCT02102165Not ApplicableRecruiting

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Role: lead

NCT00963417Not ApplicableCompleted

Study of Bone Mineral Density in Women With Breast Cancer Treated With Triptorelin and Tamoxifen or Exemestane on Protocol IBCSG 25-02

Role: collaborator

NCT00490139Phase 3Completed

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D

Role: collaborator

NCT04675827Phase 2Terminated

De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade

Role: collaborator

NCT03498716Phase 3Terminated

A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer

Role: collaborator

NCT02053636Phase 2Completed

A Phase II Trial Testing Oral Administration of Lucitanib in Patients With Fibroblast Growth Factor Receptor (FGFR)1-amplified or Non-amplified Estrogen Receptor Positive Metastatic Breast Cancer

Role: collaborator

NCT02536742Phase 2Completed

Palbociclib in Molecularly Characterized ER-positive/HER2-negative Metastatic Breast Cancer

Role: collaborator

NCT03609047Phase 2Active Not Recruiting

Adjuvant Palbociclib in Elderly Patients With Breast Cancer

Role: collaborator

NCT01864746Phase 3Completed

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

Role: collaborator

NCT01101425Unknown

Male Breast Cancer: Understanding the Biology for Improved Patient Care

Role: collaborator