Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

16.7%

5 terminated/withdrawn out of 30 trials

Success Rate

81.5%

-5.0% vs industry average

Late-Stage Pipeline

43%

13 trials in Phase 3/4

Results Transparency

9%

2 of 22 completed trials have results

Key Signals

2 recruiting2 with results

Enrollment Performance

Analytics

Phase 3
13(43.3%)
Phase 2
12(40.0%)
Phase 1
5(16.7%)
30Total
Phase 3(13)
Phase 2(12)
Phase 1(5)

Activity Timeline

Global Presence

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Clinical Trials (30)

Showing 20 of 30 trials
NCT07074002Phase 2Recruiting

Proof of Concept Study on BP1.4979 Effect on Essential Tremor

Role: lead

NCT05118906Phase 2Completed

Pilot Study on BP1.4979 Effect on Binge Eating Disorders

Role: lead

NCT07047404Phase 2Recruiting

Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation

Role: lead

NCT05953389Phase 2Active Not Recruiting

Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents

Role: lead

NCT02611687Phase 3Completed

Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period

Role: lead

NCT05240560Phase 2Terminated

Proof of Concept Study Evaluating BP1.3656 in Patients With Fatigue Following Ischemic Stroke

Role: lead

NCT03424824Phase 2Completed

Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment

Role: lead

NCT03345953Phase 2Terminated

Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome

Role: lead

NCT02739568Phase 3Completed

Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA

Role: lead

NCT00690274Phase 2Completed

Study to Demonstrate Cognitive Enhancing Effects of BF2.649

Role: collaborator

NCT02978651Phase 3Withdrawn

Pitolisant (BF2.649) in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnoea Syndrome, Treated or Not by Nasal Continuous Positive Airway Pressure, But Still Complaining of Excessive Daytime Sleepiness

Role: lead

NCT03152123Phase 1Completed

Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users

Role: lead

NCT01399606Phase 3Completed

Long Term Open Label Study in Narcolepsy With BF2.649 (Pitolisant)

Role: lead

NCT01638403Phase 3Completed

Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.

Role: lead

NCT02800083Phase 2Withdrawn

A Trial Evaluating Pitolisant (BF2.649) in Alcohol Use Disorder Treatment

Role: lead

NCT02929342Phase 1Completed

Study to Assess the Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Pitolisant in Healthy Male Volunteers

Role: lead

NCT01800045Phase 3Completed

Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)

Role: lead

NCT01789398Phase 3Completed

Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)

Role: lead

NCT01072968Phase 3Completed

BF2.649 in Patients With OSA, Still Complaining of EDS and Refusing to be Treated by CPAP.

Role: lead

NCT01785147Phase 2Completed

Efficacy and Safety of BP1.4979 in Smoking Cessation

Role: lead