Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

17.9%

30 terminated/withdrawn out of 168 trials

Success Rate

76.0%

-10.5% vs industry average

Late-Stage Pipeline

20%

34 trials in Phase 3/4

Results Transparency

63%

60 of 95 completed trials have results

Key Signals

16 recruiting60 with results25 terminated5 withdrawn

Enrollment Performance

Analytics

Phase 2
36(34.3%)
Phase 1
28(26.7%)
Phase 3
27(25.7%)
N/A
7(6.7%)
Phase 4
7(6.7%)
105Total
Phase 2(36)
Phase 1(28)
Phase 3(27)
N/A(7)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (168)

Showing 20 of 168 trials
NCT06738017Phase 1Active Not Recruiting

Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult Participants

Role: lead

NCT07441876Phase 2Recruiting

Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With Achondroplasia

Role: lead

NCT04800692Phase 1Active Not Recruiting

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

Role: collaborator

NCT06280209Phase 1Recruiting

A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy

Role: lead

NCT02597881Recruiting

Achondroplasia Natural History Multicenter Clinical Study

Role: collaborator

NCT07126262Phase 2Recruiting

A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months

Role: lead

NCT05813678Recruiting

A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

Role: lead

NCT05734196Phase 1Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

Role: collaborator

NCT05579548Recruiting

A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

Role: lead

NCT06305234Recruiting

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

Role: lead

NCT06224907Phase 3Active Not Recruiting

Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A

Role: lead

NCT07473973Phase 3Recruiting

ENERGY 2: Evaluation of the Efficacy and Safety of INZ-701 in Infants With ENPP1 Deficiency

Role: collaborator

NCT07477691Phase 4Not Yet Recruiting

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

Role: lead

NCT03424018Phase 3Active Not Recruiting

An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia

Role: lead

NCT03989947Phase 2Active Not Recruiting

An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia

Role: lead

NCT02724228Phase 2Active Not Recruiting

A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH)

Role: lead

NCT06382155Phase 2Recruiting

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Role: lead

NCT04554940Phase 2Active Not Recruiting

A Clinical Trial to Evaluate Safety of Vosoritide in At-risk Infants With Achondroplasia

Role: lead

NCT06668805Phase 2Recruiting

A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

Role: lead

NCT06455059Phase 3Active Not Recruiting

Interventional Study of Vosoritide for the Treatment of Children With Hypochondroplasia

Role: lead