Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

17.4%

4 terminated/withdrawn out of 23 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

56%

9 of 16 completed trials have results

Key Signals

9 with results

Enrollment Performance

Analytics

Phase 1
12(52.2%)
Phase 2
10(43.5%)
Phase 3
1(4.3%)
23Total
Phase 1(12)
Phase 2(10)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT03246529Phase 3Active Not Recruiting

A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)

Role: lead

NCT03281369Phase 1Completed

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Role: collaborator

NCT06547112Phase 1Completed

A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization

Role: collaborator

NCT05618301Phase 1Completed

Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

Role: collaborator

NCT05293171Phase 1Completed

Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects

Role: lead

NCT01838395Phase 2Completed

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

Role: lead

NCT03154827Phase 1Terminated

Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)

Role: lead

NCT02826486Phase 2Completed

Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients

Role: lead

NCT02639559Phase 2Completed

Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies

Role: collaborator

NCT02462252Phase 2Completed

Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

Role: lead

NCT01990885Phase 1Completed

Safety and Systemic Exposure Study of BL-7010 in Well-Controlled Celiac Patients.

Role: lead

NCT02502968Phase 2Unknown

BL-8040 Addition to Consolidation Therapy in AML Patients

Role: collaborator

NCT02073019Phase 1Completed

A Phase I Study Evaluating Safety, Tolerability, PK and PD of BL-8040 for Stem Cell Mobilization in Healthy Volunteers

Role: lead

NCT01363349Phase 2Terminated

Phase IIb-III Study of BL-1020 Small Molecule for Schizophrenia

Role: lead

NCT01833845Phase 1Terminated

Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C

Role: lead

NCT01506362Phase 2Completed

Efficacy, Pharmacodynamics, Safety and Tolerability of Oral BL-7040 in Patients With Moderately Active Ulcerative Colitis

Role: lead

NCT01121380Phase 1Terminated

A Study Intended to Evaluate Safety, Tolerability and Pharmacokinetics (PK) Parameters of BL-1021

Role: lead

NCT00557531Phase 1Unknown

Safety and Feasibility of the Injectable BL-1040 Implant

Role: lead

NCT00722176Phase 2Completed

Extension Study To Evaluate The Long-Term Safety, Tolerability, And Efficacy Of Low And High Doses Of Bl-1020

Role: lead

NCT00567710Phase 2Completed

A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study

Role: lead