Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

2.4%

2 terminated/withdrawn out of 84 trials

Success Rate

90.5%

+4.0% vs industry average

Late-Stage Pipeline

21%

18 trials in Phase 3/4

Results Transparency

5%

1 of 19 completed trials have results

Key Signals

8 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
33(40.2%)
Phase 2
31(37.8%)
Phase 3
10(12.2%)
Phase 4
8(9.8%)
82Total
Phase 1(33)
Phase 2(31)
Phase 3(10)
Phase 4(8)

Activity Timeline

Global Presence

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Clinical Trials (84)

Showing 20 of 84 trials
NCT07435038Phase 1Not Yet Recruiting

Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Role: lead

NCT07448116Phase 1Recruiting

Study of MCLA-129 in Combination With Ensartinib in Patients With Advanced Solid Tumors.

Role: lead

NCT04930432Phase 1Recruiting

Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Role: lead

NCT07181499Phase 2Recruiting

Sequential Chemotherapy With Befotertinib in Non-Small Cell Lung Cancer (NSCLC) Patients With Resistance to Third-Generation EGFR-TKI

Role: lead

NCT04206072Phase 2Completed

D-0316 Versus Icotinib in Patients With Locally Advanced or Metastatic EGFR Sensitising Mutation Positive NSCLC

Role: lead

NCT03753685Phase 2Active Not Recruiting

X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Role: collaborator

NCT06885840Phase 2Not Yet Recruiting

Study of MCLA-129 in the Treatment of Advanced Non-small Cell Lung Cancer with AGA and MET Amplification.

Role: lead

NCT05341557Phase 1Recruiting

A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Role: lead

NCT05789602Phase 1Recruiting

A Study of BPI-460372 in Advanced Solid Tumor Patients

Role: lead

NCT03791112Phase 1Active Not Recruiting

A Phase I Study of BPI-16350 in Patients with Advanced Solid Tumor

Role: lead

NCT06780839Phase 2Not Yet Recruiting

Adjuvant Treatment of ALK-positive Non-small Cell Lung Cancer with Ensartinib Guided by MRD

Role: collaborator

NCT06641609Phase 1Not Yet Recruiting

A Phase I Study of CFT8919 in Patients With Advanced NSCLC

Role: lead

NCT05341583Phase 3Recruiting

Ensartinib as Adjuvant Treatment in Anaplastic Lymphoma Kinase (ALK) Positive Non-small Cell Lung Cancer

Role: lead

NCT05007938Phase 2Active Not Recruiting

Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer

Role: lead

NCT06492525Phase 1Not Yet Recruiting

A Study To Evaluate The Effect Of Rifampicin Or Ltraconazole On Pharmacokinetics Of Ensartinib In Healthy Volunteers

Role: lead

NCT05033132Phase 2Withdrawn

A Phase II Study of Balstilimab Independently or in Combination With Zalifrelimab in Advanced Cervical Cancer

Role: collaborator

NCT06041776Phase 3Recruiting

Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations

Role: lead

NCT06015568Phase 1Not Yet Recruiting

Study of MCLA-129 Combined With Befotertinib in the Treatment of Advanced Non-small Cell Lung Cancer With EGFR Sensitive Mutation

Role: lead

NCT02959619Phase 1Completed

Ensartinib in Non-small Cell Lung Cancer Patients With Positive ALK

Role: lead

NCT03215693Phase 2Unknown

X-396 Capsule in Patients With ALK-positive Non-small Cell Lung Cancer Previously Treated With Crizotinib

Role: lead