Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

38.5%

10 terminated/withdrawn out of 26 trials

Success Rate

16.7%

-69.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

300%

6 of 2 completed trials have results

Key Signals

4 recruiting6 with results7 terminated

Enrollment Performance

Analytics

Phase 1
21(87.5%)
Phase 2
2(8.3%)
Early Phase 1
1(4.2%)
24Total
Phase 1(21)
Phase 2(2)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (26)

Showing 20 of 26 trials
NCT07164469Phase 2Not Yet Recruiting

Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma

Role: collaborator

NCT06066424Phase 1Recruiting

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Role: collaborator

NCT03721068Phase 1Recruiting

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

Role: collaborator

NCT06096038Phase 1Recruiting

Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC

Role: collaborator

NCT05620342Early Phase 1Recruiting

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

Role: collaborator

NCT03016377Phase 1Active Not Recruiting

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

Role: collaborator

NCT02414269Phase 1Active Not Recruiting

Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin

Role: collaborator

NCT02849886Phase 1Terminated

T Lymphocytes (LT) Expressing iCASP9 and ΔCD19 in Allogeneic Haematopoietic Transplantation.

Role: collaborator

NCT02231710Phase 1Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Role: lead

NCT02743611Phase 1Terminated

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

Role: lead

NCT02065869Phase 1Terminated

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Role: lead

NCT03699475Phase 2Terminated

Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS

Role: lead

NCT03733249Phase 1Terminated

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Role: lead

NCT04650451Phase 1Suspended

Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors

Role: lead

NCT01744223Phase 1Active Not Recruiting

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Role: lead

NCT03459170Phase 1Active Not Recruiting

Safety/PK Study of Gene Modified Donor T Cell Infusion in Children With Recurrent Hem Malignancies After Allo Transplant

Role: lead

NCT03301168Phase 1Active Not Recruiting

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Role: lead

NCT02477878Phase 1Active Not Recruiting

Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant

Role: lead

NCT03594162Unknown

Compassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch

Role: collaborator

NCT02786485Phase 1Withdrawn

Study of Matched Unrelated Donor T Cell Infusion for Hematologic Malignancies After Allo-HSCT

Role: lead