Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 40/100

Failure Rate

13.3%

25 terminated/withdrawn out of 188 trials

Success Rate

79.8%

-6.7% vs industry average

Late-Stage Pipeline

14%

26 trials in Phase 3/4

Results Transparency

82%

81 of 99 completed trials have results

Key Signals

26 recruiting81 with results17 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 2
80(43.2%)
Phase 1
77(41.6%)
Phase 3
25(13.5%)
Early Phase 1
2(1.1%)
Phase 4
1(0.5%)
185Total
Phase 2(80)
Phase 1(77)
Phase 3(25)
Early Phase 1(2)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (188)

Showing 20 of 188 trials
NCT07136077Phase 2Active Not Recruiting

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Role: collaborator

NCT05609370Phase 1Active Not Recruiting

A Study Investigating the Efficacy and Safety of Alcestobart (LBL-007) Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Role: lead

NCT05909904Phase 2Active Not Recruiting

A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma

Role: lead

NCT04883957Phase 1Active Not Recruiting

Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies

Role: lead

NCT03736889Phase 2Recruiting

Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors

Role: lead

NCT06558604Phase 2Recruiting

Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell Lymphoma

Role: collaborator

NCT04649385Phase 1Completed

BGB-15025 Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Participants With Advanced Solid Tumors

Role: lead

NCT03967977Phase 3Active Not Recruiting

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

Role: lead

NCT06342713Phase 1Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases

Role: lead

NCT07005713Phase 1Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of BGB-16673 in Adults With Chronic Spontaneous Urticaria

Role: lead

NCT06257264Phase 1Active Not Recruiting

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

Role: lead

NCT05542342Phase 2Completed

Sitravatinib and Tislelizumab in Patients With Metastatic Uveal Melanoma With Liver Metastases.

Role: collaborator

NCT04221542Phase 1Recruiting

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Role: collaborator

NCT07100938Phase 2Terminated

A Study Investigating the Efficacy and Safety of BGB-45035 Versus Placebo in Adults With Moderate to Severe Active Rheumatoid Arthritis

Role: lead

NCT06010303Phase 2Completed

A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Role: lead

NCT05431270Phase 1Recruiting

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

Role: collaborator

NCT04614909Early Phase 1Completed

Study of Pamiparib in Newly Diagnosed and rGBM

Role: collaborator

NCT06730542Phase 1Recruiting

Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma

Role: collaborator

NCT04746924Phase 3Terminated

A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer

Role: lead

NCT05661955Phase 1Active Not Recruiting

A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors.

Role: lead