Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

11.1%

7 terminated/withdrawn out of 63 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

29%

18 trials in Phase 3/4

Results Transparency

43%

21 of 49 completed trials have results

Key Signals

5 recruiting21 with results6 terminated

Enrollment Performance

Analytics

Phase 1
35(58.3%)
Phase 3
18(30.0%)
Phase 2
7(11.7%)
60Total
Phase 1(35)
Phase 3(18)
Phase 2(7)

Activity Timeline

Global Presence

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Clinical Trials (63)

Showing 20 of 63 trials
NCT06925321Phase 3Recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

Role: lead

NCT05421858Phase 3Recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

Role: lead

NCT06808646Phase 1Completed

A Study to Assess the Effect of Ceftobiprole on the PK of Pitavastatin and on Plasma Levels of Coproporphyrin

Role: lead

NCT07500181Phase 1Recruiting

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BAL2420 in Healthy Adult Subjects

Role: lead

NCT06961708Phase 1Completed

A Study of Fosmanogepix in Healthy Adult Chinese Subjects

Role: lead

NCT06665555Phase 1Completed

Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Participants 18 to ≤55 Years of Age

Role: lead

NCT05582187Phase 1Completed

A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.

Role: lead

NCT06733675Phase 1Recruiting

Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination

Role: lead

NCT05488678Phase 1Completed

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

Role: lead

NCT04877379Phase 1Completed

VNRX-7145 Drug-Drug Interaction in Healthy Adult Volunteers

Role: lead

NCT05527834Phase 1Completed

Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants

Role: lead

NCT04243863Phase 1Completed

VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers

Role: lead

NCT04314206Phase 1Completed

VNRX-5024 Safety and PK in Healthy Adult Volunteers

Role: lead

NCT03604705Phase 2Completed

An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia

Role: lead

NCT04148287Phase 2Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris

Role: lead

NCT04240886Phase 2Terminated

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds

Role: lead

NCT02956499Phase 1Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Role: lead

NCT02957929Phase 1Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Role: lead

NCT05856227Phase 3Completed

Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age

Role: lead

NCT06433128Unknown

Expanded Access to Fosmanogepix for Patients With Serious or Life-threatening Invasive Fungal Infections

Role: lead