Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

16.7%

4 terminated/withdrawn out of 24 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

13%

3 trials in Phase 3/4

Results Transparency

25%

4 of 16 completed trials have results

Key Signals

4 with results

Enrollment Performance

Analytics

Phase 1
17(70.8%)
Phase 2
4(16.7%)
Phase 3
3(12.5%)
24Total
Phase 1(17)
Phase 2(4)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (24)

Showing 20 of 24 trials
NCT03892018Phase 1Terminated

The Effect of Food on the Pharmacokinetics of Paclitaxel Administered Orally as Oraxol

Role: lead

NCT03544567Phase 2Completed

A Study of Oraxol in Subjects With Cutaneous Angiosarcoma

Role: lead

NCT03588039Phase 1Terminated

Study of Oraxol and Pembrolizumab in Subjects With Advanced Solid Tumors

Role: lead

NCT05487651Phase 1Unknown

Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies

Role: lead

NCT01074138Phase 2Completed

Safety and Efficacy Study of KX2-391 for Treatment of Bone-Metastatic, Castration-Resistant Prostate Cancer

Role: lead

NCT04878484Phase 1Withdrawn

Evaluate TCRT-ESO-A2 Autologous T Cells Expressing TCR Specific for NY-ESO-1 in Subjects With Advanced Solid Tumors

Role: lead

NCT02594371Phase 3Completed

Ph3 Study To Determine Safety,Tolerability&Tumor Response Of Oraxol Compared To Taxol In Metastatic Breast Cancer

Role: lead

NCT04035473Phase 1Completed

A Study to Determine the Bioequivalence of Oraxol in Cancer Patients Treated With Intravenous Paclitaxel

Role: lead

NCT04168957Phase 1Terminated

An Extension Study to Provide Oraxol to Patients Who Completed KX-ORAX-007

Role: lead

NCT02250157Phase 1Completed

A Dose-regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oratecan in Subjects With Advanced Malignancies

Role: lead

NCT03987685Phase 1Completed

Evaluate Oral Topotecan With HM30181A Monotherapy in Patients With Advanced Malignancies

Role: lead

NCT02970539Phase 1Unknown

Ph1b Study of Oraxol in Comb. w. Ramucirumab in Patients w. Gastric, Gastro-esophageal, or Esophageal Cancers

Role: lead

NCT02730481Phase 1Completed

A Study to Evaluate the Safety, Tolerability, MTD, PK, and Activity of Oraxol in Subjects w Adv. Malignancies

Role: lead

NCT04136834Phase 1Unknown

A Phase I Open-label Study for Subjects With Advanced Malignancies

Role: lead

NCT04993040Phase 1Completed

A PK Study of Oraxol in Breast Cancer Patients

Role: lead

NCT04180384Phase 2Completed

A Safety Study of Oraxol (HM30181 + Oral Paclitaxel) in Cancer Patients

Role: lead

NCT02838628Phase 2Completed

Activity & Safety Study of KX2-391 Ointment in Participants With Actinic Keratosis on the Face or Scalp

Role: collaborator

NCT03285477Phase 3Completed

A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp

Role: collaborator

NCT03285490Phase 3Completed

A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004)

Role: collaborator

NCT03575780Phase 1Completed

Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis

Role: lead