Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

17.1%

6 terminated/withdrawn out of 35 trials

Success Rate

80.6%

-5.9% vs industry average

Late-Stage Pipeline

11%

4 trials in Phase 3/4

Results Transparency

28%

7 of 25 completed trials have results

Key Signals

3 recruiting7 with results

Enrollment Performance

Analytics

Phase 1
25(73.5%)
Phase 2
5(14.7%)
Phase 3
4(11.8%)
34Total
Phase 1(25)
Phase 2(5)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (35)

Showing 20 of 35 trials
NCT07037277Phase 3Recruiting

C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV

Role: lead

NCT06911320Phase 1Recruiting

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function

Role: lead

NCT07314346Phase 1Recruiting

Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone

Role: lead

NCT07272889Phase 1Completed

Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Ethinyl Estradiol/Levonorgestrel (EE/LNG)

Role: lead

NCT06868264Phase 3Active Not Recruiting

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

Role: lead

NCT05904470Phase 2Completed

A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV

Role: lead

NCT06921941Phase 1Completed

Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Digoxin and Rosuvastatin

Role: lead

NCT07007806Phase 1Completed

Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir

Role: lead

NCT05629962Phase 3Completed

SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19

Role: lead

NCT06204679Phase 1Completed

Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir

Role: lead

NCT05724693Phase 1Completed

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Role: lead

NCT06356194Phase 1Completed

Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir

Role: lead

NCT05618314Phase 1Completed

Study of AT-527 in Subjects With Normal and Impaired Renal Function

Role: lead

NCT05466240Phase 2Terminated

Study of AT-752 in Patients With Dengue Infection

Role: lead

NCT04889040Phase 3Terminated

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19

Role: collaborator

NCT05059080Terminated

A Six-Month Follow-Up Study of Participants With Coronavirus Disease 2019 (COVID-19) Previously Enrolled in a RO7496998 (AT-527) Study

Role: collaborator

NCT05905484Phase 1Completed

Study of Bemnifosbuvir on Cardiac Repolarization in Healthy Subjects

Role: lead

NCT05905497Phase 1Completed

The Study of Bemnifosbuvir in Healthy Japanese Subjects

Role: lead

NCT05731843Phase 1Completed

Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir

Role: lead

NCT05366439Phase 1Terminated

Study of AT-752 in Healthy Subjects in a Dengue Human Challenge Model

Role: lead