Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 90/100

Failure Rate

28.6%

6 terminated/withdrawn out of 21 trials

Success Rate

71.4%

-15.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

47%

7 of 15 completed trials have results

Key Signals

7 with results6 terminated

Enrollment Performance

Analytics

Phase 1
14(66.7%)
Phase 2
7(33.3%)
21Total
Phase 1(14)
Phase 2(7)

Activity Timeline

Global Presence

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Clinical Trials (21)

Showing 20 of 21 trials
NCT06385327Phase 1Completed

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Role: lead

NCT06698575Phase 1Completed

A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in Healthy Subjects and in Subjects Seropositive for HSV-2 With Recurrent Genital Herpes

Role: lead

NCT06740474Phase 1Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in Healthy Participants

Role: lead

NCT06384131Phase 1Completed

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection

Role: lead

NCT04820686Phase 2Terminated

A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection

Role: lead

NCT04781647Phase 2Terminated

A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infection

Role: lead

NCT05569941Phase 1Completed

A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy Subjects

Role: lead

NCT05414981Phase 1Completed

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus Infection

Role: lead

NCT03780543Phase 2Terminated

A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients

Role: lead

NCT04454567Phase 2Terminated

A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitors

Role: lead

NCT04398134Phase 2Terminated

A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection

Role: lead

NCT03923478Phase 1Terminated

ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis

Role: lead

NCT03576066Phase 2Completed

A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection

Role: lead

NCT03577171Phase 2Completed

A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV)

Role: lead

NCT04271592Phase 1Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults

Role: lead

NCT03714152Phase 1Completed

A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B

Role: lead

NCT04637139Phase 1Completed

A Study to Evaluate the Mass Balance Absorption and AME of VBR

Role: lead

NCT04142762Phase 1Completed

A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults

Role: lead

NCT04083716Phase 1Completed

A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults

Role: lead

NCT02908191Phase 1Completed

A Study in Healthy Volunteers and Patients With Chronic Hepatitis B

Role: lead