Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

28.6%

2 terminated/withdrawn out of 7 trials

Success Rate

66.7%

-19.8% vs industry average

Late-Stage Pipeline

57%

4 trials in Phase 3/4

Results Transparency

75%

3 of 4 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 3

4(57.1%)

Phase 1

2(28.6%)

Phase 2

1(14.3%)

7Total

Phase 3(4)

Phase 1(2)

Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (7)

Showing 7 of 7 trials

NCT06989567Phase 3Not Yet Recruiting

A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

Role: lead

NCT05253209Phase 3Terminated

A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Role: lead

NCT04852172Phase 1Terminated

L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)

Role: lead

NCT02891837Phase 3Completed

L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects

Role: lead

NCT04570384Phase 2Completed

Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19

Role: lead

NCT01120964Phase 1Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol

Role: lead

NCT00335244Phase 3Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery

Role: lead

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