Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

7.8%

4 terminated/withdrawn out of 51 trials

Success Rate

83.3%

-3.2% vs industry average

Late-Stage Pipeline

12%

6 trials in Phase 3/4

Results Transparency

5%

1 of 20 completed trials have results

Key Signals

11 recruiting1 with results

Enrollment Performance

Analytics

Phase 1
27(52.9%)
Phase 2
17(33.3%)
Phase 3
6(11.8%)
Early Phase 1
1(2.0%)
51Total
Phase 1(27)
Phase 2(17)
Phase 3(6)
Early Phase 1(1)

Activity Timeline

Global Presence

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Clinical Trials (51)

Showing 20 of 51 trials
NCT06608927Phase 3Active Not Recruiting

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Role: lead

NCT05568095Phase 3Active Not Recruiting

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Role: lead

NCT04104672Phase 1Active Not Recruiting

A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies

Role: lead

NCT04791839Phase 2Active Not Recruiting

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Role: collaborator

NCT05536141Phase 1Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Role: lead

NCT04736173Phase 2Active Not Recruiting

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Role: lead

NCT06120075Phase 1Active Not Recruiting

A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

Role: lead

NCT07364214Phase 1Completed

Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24)

Role: lead

NCT05329766Phase 2Active Not Recruiting

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Role: lead

NCT07011719Phase 3Recruiting

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Role: lead

NCT05211895Phase 3Recruiting

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Role: collaborator

NCT04656535Early Phase 1Active Not Recruiting

AB154 Combined With AB122 for Recurrent Glioblastoma

Role: collaborator

NCT05891171Phase 1Active Not Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Role: lead

NCT05130177Phase 2Active Not Recruiting

Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma

Role: collaborator

NCT07397611Phase 2Recruiting

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

Role: collaborator

NCT05633667Phase 2Recruiting

Study of Novel Treatment Combinations in Patients With Lung Cancer

Role: collaborator

NCT07000149Phase 3Active Not Recruiting

A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Role: collaborator

NCT06727565Phase 2Active Not Recruiting

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

Role: collaborator

NCT06048484Phase 2Recruiting

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

Role: collaborator

NCT05419479Phase 1Suspended

Switch Maintenance in Pancreatic

Role: collaborator