Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 15/100

Failure Rate

11.5%

3 terminated/withdrawn out of 26 trials

Success Rate

88.0%

+1.5% vs industry average

Late-Stage Pipeline

38%

10 trials in Phase 3/4

Results Transparency

73%

16 of 22 completed trials have results

Key Signals

16 with results

Enrollment Performance

Analytics

Phase 1
8(33.3%)
Phase 4
6(25.0%)
Phase 2
6(25.0%)
Phase 3
4(16.7%)
24Total
Phase 1(8)
Phase 4(6)
Phase 2(6)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (26)

Showing 20 of 26 trials
NCT02164253Phase 2Completed

Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients

Role: collaborator

NCT02655315Phase 2Completed

Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease

Role: collaborator

NCT02728843Phase 2Completed

Study of Parkinson's Early Stage With Deferiprone

Role: lead

NCT02443545Phase 4Terminated

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Role: lead

NCT02041299Phase 4Terminated

Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias

Role: lead

NCT03802916Phase 2Completed

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload

Role: lead

NCT02174848Phase 3Completed

Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated Neurodegeneration

Role: lead

NCT01741532Phase 3Completed

Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegeneration (PKAN)

Role: lead

NCT02456558Phase 1Completed

Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects

Role: lead

NCT02189941Phase 1Completed

Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy Volunteers

Role: lead

NCT02442310Phase 1Completed

Comparison of Deferiprone Delayed Release Tablets and Deferiprone Oral Solution in Healthy Volunteers

Role: lead

NCT02465489Phase 1Completed

Comparison of Deferiprone Extended Release Tablets and Ferriprox Immediate Release Tablets in Healthy Volunteers

Role: lead

NCT00105495Phase 4Completed

Efficacy Study in Removing Excess Iron From the Heart

Role: lead

NCT01835496Phase 1Completed

Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease

Role: lead

NCT01483924Phase 2Completed

Study to Evaluate Apo805K1 in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Role: lead

NCT01989455Phase 1Completed

A Blinded, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single Doses of Intravenous Deferiprone in Healthy Volunteers

Role: lead

NCT01860703Phase 4Completed

Evaluation of Whether Deferiprone Affects QT Interval in Healthy Subjects

Role: lead

NCT01767103Phase 4Completed

An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild and Moderate Hepatic Insufficiency and Healthy Volunteers

Role: lead

NCT01770652Phase 4Completed

An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild, Moderate, Severe, or No Renal Impairment

Role: lead

NCT02191657Phase 1Completed

Antiretroviral Activity and Pharmacokinetics of Deferiprone in Healthy Volunteers and Asymptomatic HIV-infected Subjects

Role: lead