Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

0.0%

0 terminated/withdrawn out of 18 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

56%

10 trials in Phase 3/4

Results Transparency

0%

0 of 14 completed trials have results

Key Signals

2 recruiting

Enrollment Performance

Analytics

Phase 3
9(52.9%)
Phase 1
4(23.5%)
Phase 2
3(17.6%)
Phase 4
1(5.9%)
17Total
Phase 3(9)
Phase 1(4)
Phase 2(3)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (18)

Showing 18 of 18 trials
NCT06350032Phase 3Recruiting

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

Role: lead

NCT06514807Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythaemia Patients

Role: lead

NCT03003325Phase 2Completed

The Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV

Role: collaborator

NCT06445673Enrolling By Invitation

A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) Patients

Role: lead

NCT06317805Phase 4Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients

Role: lead

NCT03117816Phase 3Completed

ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission

Role: collaborator

NCT02218047Phase 3Completed

AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.

Role: lead

NCT01933906Phase 1Completed

Addition of P1101 to Imatinib Treatment in Patients With Chronic Phase Chronic Myeloid Leukaemia Not Achieving a Complete Molecular Response

Role: collaborator

NCT01193699Phase 1Completed

Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera

Role: lead

NCT01949805Phase 3Completed

Pegylated Interferon Alpha-2b Versus Hydroxyurea in Polycythemia Vera

Role: lead

NCT01230775Phase 3Completed

Anagrelide Retard vs. Placebo: Efficacy and Safety in "At-risk" Patients With Essential Thrombocythaemia

Role: lead

NCT02523638Phase 3Completed

Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera Patients

Role: lead

NCT02076815Phase 3Completed

Anagrelide Retard in Essential Thrombocythemia

Role: lead

NCT01741519Phase 1Completed

Long-term PK and Safety/Tolerability Testing LDLL600 Against Esmolol in Healthy Volunteers

Role: lead

NCT01652898Phase 1Completed

A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy Volunteers

Role: lead

NCT01313143Phase 2Completed

A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. Esmolol

Role: lead

NCT01065038Phase 3Completed

Anagrelide vs. Hydroxyurea - Efficacy and Tolerability Study in Patients With Essential Thrombocythaemia

Role: lead

NCT00671736Phase 2Completed

Lancovutide (Moli1901) Inhalation Solution Study in Adolescents and Adults With Cystic Fibrosis

Role: lead

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