Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

38.9%

7 terminated/withdrawn out of 18 trials

Success Rate

61.1%

-25.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

100%

11 of 11 completed trials have results

Key Signals

11 with results

Enrollment Performance

Analytics

Phase 1
15(88.2%)
Phase 2
2(11.8%)
17Total
Phase 1(15)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (18)

Showing 18 of 18 trials
NCT04290546Phase 1Completed

CIML NK Cell in Head & Neck Cancer

Role: collaborator

NCT02523469Phase 1Completed

ALT-803 Plus Nivolumab in Patients With Pretreated, Advanced or Metastatic Non-Small Cell Lung Cancer

Role: collaborator

NCT03381586Phase 1Completed

QUILT-1.004: A Single Center, Open-label, Pharmacokinetic Study of Subcutaneous ALT-803

Role: lead

NCT01946789Phase 1Completed

A Phase 1 Study of the Clinical and Immunologic Effects of ALT-803 in Patients With Advanced Solid Tumors

Role: lead

NCT01438853Phase 1Completed

Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome

Role: lead

NCT04142359Terminated

PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14)

Role: lead

NCT02099539Phase 1Terminated

QUILT-3.005: A Study of N-803 in Patients With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT01625260Phase 1Terminated

A Study of ALT-801 in Patients With Bacillus Calmette-Guerin (BCG) Failure Non-Muscle Invasive Bladder Cancer

Role: lead

NCT02384954Phase 1Terminated

QUILT-3.002: N-803 in Patients With Relapse/Refractory iNHL in Conjunction With Rituximab

Role: lead

NCT01326871Phase 1Completed

A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer

Role: lead

NCT01670994Phase 1Terminated

QUILT-3.020: A Study of ALT-801 in Patients With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT03003728Phase 2Withdrawn

2015-10: Expanded Natural Killer Cells and Elotuzumab for High-Risk Myeloma Post- Autologous Stem Cell Transplant (ASCT)

Role: collaborator

NCT02559674Phase 1Completed

QUILT-2.001: ALT-803 in Patients With Advanced Pancreatic Cancer in Conjunction With Gemcitabine and Nab-Paclitaxel

Role: lead

NCT01029873Phase 1Completed

QUILT-2.008: Study of ALT-801 With Cisplatin in Patients With Metastatic Melanoma

Role: lead

NCT01325558Phase 1Completed

A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors

Role: lead

NCT00879606Phase 2Completed

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Role: lead

NCT01478074Phase 1Withdrawn

ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia

Role: lead

NCT00496860Phase 1Completed

Safety and Efficacy Study of ALT-801 to Treat Progressive Metastatic Malignancies

Role: lead

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