Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

12.5%

1 terminated/withdrawn out of 8 trials

Success Rate

75.0%

-11.6% vs industry average

Late-Stage Pipeline

0 trials in Phase 3/4

Results Transparency

33%

1 of 3 completed trials have results

Key Signals

1 recruiting1 with results

Enrollment reporting

Analytics

Phase 1

4(57.1%)

Phase 2

2(28.6%)

Phase 1/2

1(14.3%)

7Total

Phase 1(4)

Phase 2(2)

Phase 1/2(1)

Activity Timeline

Global Presence

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Clinical Trials (8)

Showing 8 of 8 trials

NCT06514794Phase 2Recruiting

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Role: lead

NCT05377827Phase 1Suspended

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Role: collaborator

NCT03068819Phase 1/2Completed

Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell Transplant

Role: collaborator

NCT04984356Phase 1Completed

A Phase 1 Study of of Anti-CD7 Allogeneic CAR-T Cell Therapy (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBL

Role: lead

NCT05470140Phase 1Completed

A Phase 1 Study of WU-NK-101 in Patients With Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)

Role: lead

NCT05674526Phase 1Active Not Recruiting

A Phase 1b Study of WU-NK-101 in Combination With Cetuximab

Role: lead

NCT05509855Enrolling By Invitation

A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007

Role: lead

NCT04893915Phase 2Withdrawn

Cytokine-induced Memory-like NK Cells in Relapsed/Refractory AML and MDS

Role: collaborator

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