Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

16.7%

3 terminated/withdrawn out of 18 trials

Success Rate

83.3%

-3.2% vs industry average

Late-Stage Pipeline

22%

4 trials in Phase 3/4

Results Transparency

67%

10 of 15 completed trials have results

Key Signals

10 with results

Enrollment Performance

Analytics

Phase 1
7(38.9%)
Phase 2
7(38.9%)
Phase 3
4(22.2%)
18Total
Phase 1(7)
Phase 2(7)
Phase 3(4)

Activity Timeline

Global Presence

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Clinical Trials (18)

Showing 18 of 18 trials
NCT06577116Phase 1Completed

Open-Label Extension Study for Subjects With H1 Antihistamine Refractory Chronic Spontaneous Urticaria Completing Study AK006-001

Role: lead

NCT06072157Phase 1Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria

Role: lead

NCT05155085Phase 2Terminated

A Study to Assess Subcutaneous Lirentelimab (AK002) in Atopic Dermatitis

Role: lead

NCT05528861Phase 2Terminated

A Study to Assess Subcutaneous Lirentelimab (AK002) in Chronic Spontaneous Urticaria

Role: lead

NCT04620811Phase 3Completed

An Extension Study of Lirentelimab in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

Role: lead

NCT03436797Phase 2Completed

A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic Urticaria

Role: lead

NCT03664960Phase 2Completed

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Role: lead

NCT03496571Phase 2Completed

A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Role: lead

NCT04322708Phase 2Completed

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

Role: lead

NCT04322604Phase 3Completed

A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

Role: lead

NCT04856891Phase 3Completed

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis

Role: lead

NCT04324268Phase 1Completed

A Study to Evaluate Safety, Tolerability, and Bioavailability of Subcutaneous Lirentelimab (AK002) in Adult Healthy Volunteers

Role: lead

NCT05152563Phase 3Withdrawn

A Study to Assess Subcutaneous AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Role: lead

NCT02734849Phase 2Completed

Study to Evaluate Multiple Doses in Patients With Nasal Polyposis

Role: lead

NCT03379311Phase 1Completed

A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis

Role: lead

NCT02808793Phase 1Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK002

Role: lead

NCT02859701Phase 1Completed

Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AK002 in Healthy Participants

Role: lead

NCT02563938Phase 1Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK001

Role: lead

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