Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

4.6%

7 terminated/withdrawn out of 153 trials

Success Rate

88.3%

+1.8% vs industry average

Late-Stage Pipeline

23%

35 trials in Phase 3/4

Results Transparency

0%

0 of 53 completed trials have results

Key Signals

42 recruiting7 terminated

Enrollment Performance

Analytics

Phase 1
66(43.4%)
Phase 2
51(33.6%)
Phase 3
35(23.0%)
152Total
Phase 1(66)
Phase 2(51)
Phase 3(35)

Activity Timeline

Global Presence

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Clinical Trials (153)

Showing 20 of 153 trials
NCT07566247Phase 1Not Yet Recruiting

A Phase I Clinical Study of AK150 in Advanced Malignant Solid Tumor

Role: lead

NCT07560124Phase 1Not Yet Recruiting

A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Breast Cancer

Role: lead

NCT07547787Recruiting

A Long-term Follow-up Study of Subjects Enrolled in Clinical Trials of Cadonilimab (AK104)

Role: lead

NCT05951608Phase 1Active Not Recruiting

A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid Tumors

Role: lead

NCT07412613Phase 3Recruiting

Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer

Role: lead

NCT06928389Phase 3Recruiting

Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT07502222Phase 2Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of AK139 in Patients With Moderate-to-severe Atopic Dermatitis

Role: lead

NCT06396065Phase 3Active Not Recruiting

Phase III Study of AK112 for NSCLC Patients

Role: collaborator

NCT06378697Phase 3Completed

A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

Role: lead

NCT05689853Phase 1Recruiting

Study of AK119 Combined With AK112 in Patients With Advanced Solid Tumors

Role: lead

NCT06700499Phase 2Completed

A Study to Evaluate the Efficacy and Safety of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Role: lead

NCT06767527Phase 3Recruiting

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Role: lead

NCT07052253Phase 2Recruiting

A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.

Role: lead

NCT05227664Phase 2Active Not Recruiting

A Study of AK117/AK112 in Metastatic Triple-Negative Breast Cancer

Role: lead

NCT05229497Phase 1Active Not Recruiting

A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors

Role: lead

NCT05904379Phase 1Active Not Recruiting

AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer

Role: lead

NCT06646055Phase 1Active Not Recruiting

AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer

Role: lead

NCT05499390Phase 3Active Not Recruiting

AK112 in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT07340476Phase 1Active Not Recruiting

A Study to Evaluate the PK Similarity of AK112 in Healthy Chinese Male Subjects

Role: lead

NCT06951646Phase 2Recruiting

ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)

Role: collaborator