Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

4.4%

7 terminated/withdrawn out of 160 trials

Success Rate

89.1%

+2.5% vs industry average

Late-Stage Pipeline

23%

36 trials in Phase 3/4

Results Transparency

0%

0 of 57 completed trials have results

Key Signals

46 recruiting7 terminated

Enrollment Performance

Analytics

Phase 1
68(42.8%)
Phase 2
55(34.6%)
Phase 3
36(22.6%)
159Total
Phase 1(68)
Phase 2(55)
Phase 3(36)

Activity Timeline

Global Presence

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Clinical Trials (160)

Showing 20 of 160 trials
NCT07162714Phase 2Recruiting

SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer

Role: collaborator

NCT05247684Phase 2Active Not Recruiting

AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC

Role: lead

NCT07623356Phase 1Recruiting

A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT06396065Phase 3Active Not Recruiting

Phase III Study of AK112 for NSCLC Patients

Role: collaborator

NCT07591090Phase 2Recruiting

A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer

Role: lead

NCT07700979Phase 3Not Yet Recruiting

Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma

Role: lead

NCT07669779Phase 2Recruiting

A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT05256472Phase 2Completed

A Study of AK104 Monotherapy or AK104 Plus Axitinib in Advanced/Metastatic Renal Cell Carcinoma

Role: lead

NCT07043283Phase 1Completed

A Study Evaluating the Single Subcutaneous Injection of Ebronucimab in Healthy Male Chinese Subjects

Role: lead

NCT05235542Phase 1Completed

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Role: lead

NCT05215067Phase 2Completed

A Phase II Trial of AK104 in Advanced Non-Small Cell Lung Cancer

Role: lead

NCT07636772Phase 2Not Yet Recruiting

A Phase II Study of AK146D1 Mono or Combined With AK112 in Advanced Urothelial Carcinoma

Role: lead

NCT07635290Phase 2Active Not Recruiting

Anlotinib+Cadonilimab+PULSAR in Advanced Biliary Tract Cancer

Role: collaborator

NCT07619001Phase 1Not Yet Recruiting

A Study to Evaluate the PK Similarity of AK104 in Healthy Chinese Male Participations

Role: lead

NCT07566247Phase 1Not Yet Recruiting

A Phase I Clinical Study of AK150 in Advanced Malignant Solid Tumor

Role: lead

NCT07560124Phase 1Not Yet Recruiting

A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Breast Cancer

Role: lead

NCT07547787Recruiting

A Long-term Follow-up Study of Subjects Enrolled in Clinical Trials of Cadonilimab (AK104)

Role: lead

NCT05951608Phase 1Active Not Recruiting

A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid Tumors

Role: lead

NCT07412613Phase 3Recruiting

Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer

Role: lead

NCT06928389Phase 3Recruiting

Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer

Role: lead