Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

18.2%

12 terminated/withdrawn out of 66 trials

Success Rate

78.2%

-8.4% vs industry average

Late-Stage Pipeline

11%

7 trials in Phase 3/4

Results Transparency

63%

27 of 43 completed trials have results

Key Signals

6 recruiting27 with results6 terminated6 withdrawn

Enrollment Performance

Analytics

Phase 2

26(53.1%)

Phase 1

9(18.4%)

N/A

6(12.2%)

Phase 3

6(12.2%)

Phase 4

1(2.0%)

Early Phase 1

1(2.0%)

49Total

Phase 2(26)

Phase 1(9)

N/A(6)

Phase 3(6)

+2 more

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (66)

Showing 20 of 66 trials

NCT05077527Phase 1Recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

Role: lead

NCT03603808Phase 2Completed

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Role: lead

NCT07662928Phase 2Not Yet Recruiting

Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK Study

Role: lead

NCT04483726Not ApplicableCompleted

Distal Pancreatectomy, Minimally Invasive or Open, for Malignancy (DIPLOMA)

Role: collaborator

NCT04949464Not ApplicableRecruiting

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

Role: lead

NCT04139304Early Phase 1Recruiting

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Role: lead

NCT05663502Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

Role: lead

NCT02799485Phase 2Completed

sEphB4-HSA in Treating Patients With Kaposi Sarcoma

Role: lead

NCT07539454Phase 2Not Yet Recruiting

Nirogacestat in Patients With Kaposi Sarcoma

Role: lead

NCT02797470Phase 1Active Not Recruiting

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

Role: lead

NCT02437851Phase 2Completed

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

Role: lead

NCT03601806Phase 2Completed

Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection

Role: lead

NCT05510908Completed

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

Role: lead

NCT04704648Not ApplicableRecruiting

Feasibility Study of Ocular Surface Squamous Neoplasia Surgical Excision in People Living With HIV in Sub-Saharan Africa

Role: lead

NCT04305691Phase 2Recruiting

Trial of Ixazomib for Kaposi Sarcoma

Role: lead

NCT03596918Completed

Evaluating Quality of Life in Patients With AIDS-Associated Kaposi Sarcoma Treated With Bleomycin and Vincristine

Role: lead

NCT05784415Completed

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

Role: lead

NCT03284866Phase 3Completed

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV

Role: lead

NCT05411237Phase 3Not Yet Recruiting

Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma

Role: lead

NCT05797662Phase 2Not Yet Recruiting

A Study of Propranolol to Treat Kaposi Sarcoma

Role: lead