Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

10.0%

2 terminated/withdrawn out of 20 trials

Success Rate

90.0%

+3.5% vs industry average

Late-Stage Pipeline

10%

2 trials in Phase 3/4

Results Transparency

28%

5 of 18 completed trials have results

Key Signals

5 with results

Enrollment Performance

Analytics

Phase 2
12(60.0%)
Phase 1
6(30.0%)
Phase 3
2(10.0%)
20Total
Phase 2(12)
Phase 1(6)
Phase 3(2)

Activity Timeline

Global Presence

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Clinical Trials (20)

Showing 20 of 20 trials
NCT03536039Phase 2Completed

RCHOP Chemoimmunotherapy Preceded BY BBB Permeabilization by t-NGR Necrosis Factor

Role: collaborator

NCT00419328Phase 1Completed

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

Role: lead

NCT04097301Phase 1Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Role: lead

NCT00914628Phase 3Terminated

Efficacy Study on the Strategy of HSV-Tk Engineering Donor Lymphocytes to Treat Patients With High Risk Acute Leukemia

Role: lead

NCT00483509Phase 2Completed

Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Metastatic Small Cell Lung Carcinoma

Role: lead

NCT00305084Phase 1Completed

Study of NGR-hTNF in Combination With Doxorubicin in Solid Tumors

Role: lead

NCT01098266Phase 3Completed

NGR015: Study in Second Line for Patient With Advanced Malignant Pleural Mesothelioma Pretreated With Pemetrexed

Role: lead

NCT00483080Phase 2Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Colorectal Cancer (CRC)

Role: lead

NCT00484276Phase 2Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma

Role: lead

NCT01358084Phase 2Completed

Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced MPM

Role: lead

NCT03804866Phase 2Completed

NGR-hTNF in Combination With an Anthracycline in Platinum-resistant Ovarian Cancer (NGR018)

Role: lead

NCT01358071Phase 2Completed

Phase II Study of NGR-hTNF in Combination With Doxorubicin in Platinum-resistant Ovarian Cancer

Role: lead

NCT00484432Phase 2Completed

Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Advanced or Metastatic Ovarian Cancer

Role: lead

NCT00994097Phase 2Completed

NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung Cancer

Role: lead

NCT00878111Phase 1Completed

Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid Tumour

Role: lead

NCT00484341Phase 2Completed

Phase II Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas.

Role: lead

NCT00423124Phase 1Completed

Infusion of Donor Lymphocytes Transduced With the Suicide Gene HSV TK in Patients With Haematological Malignancies

Role: lead

NCT00675012Phase 2Completed

NGR-hTNF Administered in Combination With a Standard Oxaliplatin Based Regimen in Patients With Metastatic Colorectal Cancer

Role: lead

NCT00483093Phase 1Completed

Study of NGR-hTNF in Combination With Cisplatin in Solid Tumor

Role: lead

NCT00484211Phase 2Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Role: lead

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