Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 75/100

Failure Rate

20.0%

4 terminated/withdrawn out of 20 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 16 completed trials have results

Key Signals

Enrollment Performance

Analytics

Phase 1
12(85.7%)
Phase 2
2(14.3%)
14Total
Phase 1(12)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (20)

Showing 20 of 20 trials
NCT02508896Phase 1Completed

Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects

Role: lead

NCT02618941Phase 1Completed

Follow-up Study to Assess a Second Boost Immunization With AFFITOPE® PD01A With Regard to Safety and Clinical Activity (AFF008AA)

Role: lead

NCT02270489Phase 1Completed

Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA

Role: lead

NCT02267434Phase 1Completed

Study Assessing Tolerability and Safety of AFFITOPE® PD03A in Patients With Early Parkinson's Disease

Role: lead

NCT02758730Phase 1Withdrawn

Study Assessing Tolerability and Safety and Exploring the Immunogenicity and Therapeutic Activity of AFFITOPE® PD01A in PD-GBA Patients

Role: lead

NCT01885494Completed

AFF008E: Observational Phase 1b Follow-up Extension Study for Patients With Parkinson's Disease After Immunization With AFFITOPE® PD01A

Role: lead

NCT02216188Phase 1Completed

Follow-up Study to Assess One Boost Immunization With AFFITOPE® PD01A With Regard to Safety and Clinical Activity

Role: lead

NCT01568099Phase 1Completed

Tolerability and Safety of Subcutaneous Administration of Two Doses of AFFITOPE® PD01A in Early Parkinson's Disease

Role: lead

NCT02008513Phase 2Terminated

Follow-up Study to Assess Safety and Clinical Activity of Continued AFFITOPE® AD02 Vaccinations of Patients Who Participated in AFF006

Role: lead

NCT01357629Terminated

Observational Follow-up Extension Study of AFF002 and AFF004A in Patients With Alzheimer's Disease

Role: lead

NCT01117818Phase 2Completed

Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease

Role: lead

NCT01568086Terminated

Follow-up Study to Evaluate Long-term Safety and Tolerability of Immunization With AD03 Applied During AFF005A

Role: lead

NCT01284582Phase 1Completed

Safety, Immunogenicity and Dose Response of ATH03, a New Vaccine Against the Cholesterol Ester Transfer Protein (CETP)

Role: lead

NCT01309763Phase 1Completed

Safety and Tolerability of AFFITOPE AD03

Role: lead

NCT01225809Completed

AD01 Follow up Extension Visit

Role: lead

NCT00495417Phase 1Completed

Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease

Role: lead

NCT01093664Phase 1Completed

Safety/Tolerability, Immunological and Clinical Activity of a Boost Immunization With AFFITOPE AD02

Role: lead

NCT00633841Phase 1Completed

Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease

Role: lead

NCT00711139Completed

Long-term Safety and Tolerability of AFFITOPE AD01

Role: lead

NCT00711321Completed

Long-term Safety and Tolerability of AFFITOPE AD02

Role: lead

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