Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

63.6%

7 terminated/withdrawn out of 11 trials

Success Rate

36.4%

-50.1% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

100%

4 of 4 completed trials have results

Key Signals

4 with results7 terminated

Enrollment Performance

Analytics

Phase 1
8(72.7%)
Phase 2
3(27.3%)
11Total
Phase 1(8)
Phase 2(3)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT05109442Phase 1Terminated

Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers

Role: lead

NCT05883449Phase 2Terminated

Phase 2 Study of AFM13 in Combination With AB-101 in Subjects With R/R HL and CD30+ PTCL

Role: lead

NCT05817058Phase 1Terminated

First-in-Human Dose Escalation Study of AFM28 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Role: lead

NCT04259450Phase 1Terminated

Study to Assess AFM24 in Advanced Solid Cancers

Role: lead

NCT04101331Phase 2Completed

Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides

Role: lead

NCT05099549Phase 1Terminated

Safety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing Cancers

Role: collaborator

NCT02321592Phase 2Completed

GHSG-AFM13 An Open-label, Multicenter Phase II Trial With AFM13 in Patients With Relapsed or Refractory Hodgkin Lymphoma

Role: collaborator

NCT02848911Phase 1Terminated

Safety Study to Assess AFM11 in Patients With Relapsed or Refractory Adult B-precursor ALL

Role: lead

NCT02106091Phase 1Terminated

Safety Study to Assess AFM11 in Patients With Relapsed and/or Refractory CD19 Positive B-cell NHL

Role: lead

NCT02665650Phase 1Completed

Study of the Combination of AFM13 and Pembrolizumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Role: lead

NCT01221571Phase 1Completed

A Study to Assess AFM13 in Patients With Hodgkin Lymphoma

Role: lead

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