Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

11.9%

5 terminated/withdrawn out of 42 trials

Success Rate

88.1%

+1.6% vs industry average

Late-Stage Pipeline

24%

10 trials in Phase 3/4

Results Transparency

19%

7 of 37 completed trials have results

Key Signals

7 with results

Enrollment Performance

Analytics

Phase 1
16(38.1%)
Phase 2
14(33.3%)
Phase 3
10(23.8%)
N/A
2(4.8%)
42Total
Phase 1(16)
Phase 2(14)
Phase 3(10)
N/A(2)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (42)

Showing 20 of 42 trials
NCT04786873Phase 3Completed

A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is

Role: lead

NCT01614990Phase 2Completed

Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia

Role: collaborator

NCT02238496Phase 1Completed

Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

Role: collaborator

NCT00448747Phase 3Completed

Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.

Role: lead

NCT00449150Phase 3Terminated

Cetrorelix (CET) Pamoate Regimens in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)

Role: lead

NCT01767155Phase 3Completed

Zoptarelin Doxorubicin (AEZS 108) as Second Line Therapy for Endometrial Cancer

Role: lead

NCT01048580Phase 1Completed

Study of Perifosine + Capecitabine for Colon Cancer Patients

Role: lead

NCT02558829Phase 3Completed

Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency

Role: lead

NCT00847366Not ApplicableCompleted

Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma

Role: lead

NCT00398710Phase 2Completed

A Phase II Study of Perifosine in Patients With Relapsed/Refractory Waldenström's Macroglobulinemia

Role: lead

NCT01234519Phase 1Terminated

A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy

Role: lead

NCT01224730Phase 1Completed

A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies

Role: lead

NCT00398879Phase 2Completed

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Role: lead

NCT00391560Phase 2Completed

Phase II Study of Perifosine in Patients With Refractory and Relapsed Leukemia

Role: lead

NCT00401388Phase 2Completed

A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas

Role: lead

NCT00389077Phase 2Completed

Trial of Two Schedules of Perifosine for Patients With Solid Tumors or Lymphomas

Role: lead

NCT00448721Phase 2Completed

A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer

Role: lead

NCT00375791Phase 2Completed

Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma

Role: lead

NCT00401011Phase 1Completed

Safety & Efficacy Study of Perifosine + Bortezomib +/- Dexamethasone for Multiple Myeloma Patients

Role: lead

NCT00399789Phase 1Completed

A Phase 1/2 Trial of Perifosine in the Treatment of Non-Small Cell Lung Cancer

Role: lead