Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

46.2%

6 terminated/withdrawn out of 13 trials

Success Rate

53.8%

-32.7% vs industry average

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

114%

8 of 7 completed trials have results

Key Signals

8 with results

Enrollment Performance

Analytics

Phase 1
7(53.8%)
Phase 2
5(38.5%)
Phase 3
1(7.7%)
13Total
Phase 1(7)
Phase 2(5)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (13)

Showing 13 of 13 trials
NCT03847519Phase 1Completed

Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer

Role: lead

NCT02164461Phase 1Completed

Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer

Role: lead

NCT02325557Phase 1Completed

ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Role: lead

NCT02531854Phase 2Withdrawn

A Study of Pemetrexed Maintenance With or Without ADXS11-001 Immunotherapy in Patients With Human Papillomavirus Positive (HPV+), NSCLC Following First-Line Induction Chemotherapy

Role: lead

NCT02399813Phase 2Completed

A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal

Role: lead

NCT02291055Phase 1Terminated

A Study of ADXS11-001 or MEDI4736 Alone or Combination In Cervical or Human Papillomavirus (HPV)+ Head & Neck Cancer

Role: lead

NCT02853604Phase 3Terminated

Study of ADXS11-001 in Participants With High Risk Locally Advanced Cervical Cancer

Role: lead

NCT03265080Phase 1Terminated

A Study of ADXS-NEO Expressing Personalized Tumor Antigens

Role: lead

NCT02002182Phase 2Completed

ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer

Role: collaborator

NCT01266460Phase 2Completed

Vaccine Therapy in Treating Patients With Persistent or Recurrent Cervical Cancer

Role: collaborator

NCT02386501Phase 1Completed

Dose Escalation Study of ADXS31-164 in Subjects With HER2 Expressing Solid Tumors

Role: lead

NCT01116245Phase 2Terminated

An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+

Role: lead

NCT01598792Phase 1Terminated

Safety Study of Recombinant Listeria Monocytogenes(Lm)Based Vaccine Virus Vaccine to Treat Oropharyngeal Cancer

Role: collaborator

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