Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

23.1%

9 terminated/withdrawn out of 39 trials

Success Rate

60.9%

-25.6% vs industry average

Late-Stage Pipeline

10%

4 trials in Phase 3/4

Results Transparency

79%

11 of 14 completed trials have results

Key Signals

4 recruiting11 with results8 terminated

Enrollment Performance

Analytics

Phase 2
15(46.9%)
Phase 1
13(40.6%)
Phase 3
3(9.4%)
Phase 4
1(3.1%)
32Total
Phase 2(15)
Phase 1(13)
Phase 3(3)
Phase 4(1)

Activity Timeline

Global Presence

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Clinical Trials (39)

Showing 20 of 39 trials
NCT03872778Phase 1Completed

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake

Role: lead

NCT04375267Phase 1Completed

177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours

Role: collaborator

NCT05249114Phase 1Active Not Recruiting

Study of Cabozantinib With Lu-177 in Patients With Somatostatin Receptor 2 Positive Neuroendocrine Tumors

Role: collaborator

NCT04069299Completed

Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract

Role: collaborator

NCT06388369Phase 1Terminated

Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer

Role: collaborator

NCT04443062Phase 2Completed

Lutetium-177-PSMA-617 in Oligo-metastatic Hormone Sensitive Prostate Cancer

Role: collaborator

NCT04711135Phase 2Active Not Recruiting

Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs

Role: lead

NCT03972488Phase 3Active Not Recruiting

Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET

Role: lead

NCT03691064Active Not Recruiting

Post-Authorization Long-Term Safety Study of LUTATHERA

Role: lead

NCT05162573Phase 1Completed

EBRT + Lu-PSMA for N1M0 Prostate Cancer

Role: collaborator

NCT05178693Phase 1Recruiting

Lutathera and ASTX727 in Neuroendocrine Tumours

Role: collaborator

NCT04529044Phase 2Not Yet Recruiting

177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer

Role: collaborator

NCT05885009Recruiting

Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102)

Role: collaborator

NCT04837885Phase 2Recruiting

Intra-arterial Hepatic (IAH) Infusion of Radiolabelled Somatostatin Analogs in GEP-NET Patients With Dominant Liver Metastases

Role: collaborator

NCT04343885Phase 2Active Not Recruiting

In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy

Role: collaborator

NCT03490838Phase 1Terminated

177Lu-PSMA-R2 in Patients With PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer

Role: lead

NCT02230176Phase 2Completed

Antitumor Efficacy of Peptide Receptor Radionuclide Therapy With 177Lutetium -Octreotate Randomized vs Sunitinib in Unresectable Progressive Well-differentiated Neuroendocrine Pancreatic Tumor: First Randomized Phase II

Role: collaborator

NCT04903899Phase 2Recruiting

177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma

Role: collaborator

NCT04524442Phase 4Completed

Post-Authorization Safety Study (PASS) of LysaKare® in Adult Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) Patients

Role: lead

NCT06783348Phase 2Not Yet Recruiting

Radiopharmaceutical Treatment of Advanced Kidney Cancer

Role: collaborator