Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

50.0%

6 terminated/withdrawn out of 12 trials

Success Rate

50.0%

-36.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

150%

9 of 6 completed trials have results

Key Signals

9 with results6 terminated

Enrollment Performance

Analytics

Phase 2
7(58.3%)
Phase 1
5(41.7%)
12Total
Phase 2(7)
Phase 1(5)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT03376477Phase 2Terminated

Allogeneic Myeloma GM-CSF Vaccine With Lenalidomide in Multiple Myeloma Patients in Complete or Near Complete Remission

Role: collaborator

NCT03190265Phase 2Completed

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

Role: collaborator

NCT02243371Phase 2Completed

GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab

Role: collaborator

NCT03189030Phase 1Terminated

Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer

Role: lead

NCT01675765Phase 1Completed

Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

Role: lead

NCT03674502Phase 1Terminated

Safety of ADU-1604 in Adults With Metastatic Melanoma

Role: lead

NCT03122548Phase 2Terminated

Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal Cancers

Role: lead

NCT02575807Phase 1Terminated

Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian or Peritoneal Cancer

Role: lead

NCT03175172Phase 2Terminated

Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)

Role: lead

NCT01967758Phase 1Completed

Phase I Study of Safety and Immunogenicity of ADU-623

Role: collaborator

NCT02004262Phase 2Completed

Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting

Role: lead

NCT01417000Phase 2Completed

Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancer

Role: lead

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