Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

53.3%

8 terminated/withdrawn out of 15 trials

Success Rate

38.5%

-48.0% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

140%

7 of 5 completed trials have results

Key Signals

1 recruiting7 with results7 terminated

Enrollment Performance

Analytics

Phase 1
11(84.6%)
Phase 2
2(15.4%)
13Total
Phase 1(11)
Phase 2(2)

Activity Timeline

Global Presence

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Clinical Trials (15)

Showing 15 of 15 trials
NCT02989064Phase 1Completed

MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers

Role: lead

NCT02592577Phase 1Completed

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

Role: lead

NCT06204991Phase 1Recruiting

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma

Role: collaborator

NCT03132792Phase 1Active Not Recruiting

AFPᶜ³³²T in Advanced HCC

Role: lead

NCT02636855Completed

Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination

Role: lead

NCT04526509Phase 1Terminated

Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors

Role: lead

NCT05943990Phase 1Terminated

Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Role: lead

NCT06048705Phase 1Terminated

Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer

Role: lead

NCT04752358Phase 2Terminated

ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2)

Role: lead

NCT04408898Phase 2Withdrawn

SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer

Role: lead

NCT03391791Terminated

Long Term Follow up of Subjects Exposed to Genetically Engineered T Cell Receptors

Role: lead

NCT00991224Phase 1Completed

Redirected High Affinity Gag-Specific Autologous T Cells for HIV Gene Therapy

Role: collaborator

NCT01567891Phase 1Completed

CT Antigen TCR-redirected T Cells for Ovarian Cancer.

Role: lead

NCT01350401Phase 1Terminated

Phase I/II Study to Assess the Safety and Activity of Enhanced TCR Transduced Autologous T Cells in Metastatic Melanoma

Role: lead

NCT01892293Phase 1Terminated

CT Antigen TCR-Engineered T Cells for Myeloma

Role: lead

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