Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 60/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

80.0%

-6.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed trials have results

Key Signals

4 recruiting

Enrollment Performance

Analytics

Phase 1
11(91.7%)
Phase 2
1(8.3%)
12Total
Phase 1(11)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT04524871Phase 1Recruiting

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Role: collaborator

NCT04501276Phase 1Completed

A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients

Role: lead

NCT05614258Phase 1Active Not Recruiting

Study of ADG206 in Subjects With Advanced/Metastatic Solid Tumors

Role: lead

NCT05405595Phase 1Recruiting

ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

Role: lead

NCT06846268Phase 2Recruiting

Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer

Role: collaborator

NCT05275777Phase 1Active Not Recruiting

A Phase Ib Safety lead-in, Followed by Phase II Trial of ADG106 in Combination With Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer

Role: collaborator

NCT05491083Phase 1Recruiting

Pembrolizumab and ADG106 in Advanced Solid Cancers and Triple Negative Breast Cancer

Role: collaborator

NCT04645069Phase 1Completed

ADG126, ADG126 in Combination With Anti PD1 Antibody, and ADG126 in Combination With ADG106 in Advanced/Metastatic Solid Tumors

Role: lead

NCT05277402Phase 1Completed

ADG116 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

Role: lead

NCT03707093Phase 1Completed

Study of CD137 Agonist ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma

Role: lead

NCT05236608Phase 1Unknown

A Study to Evaluate the Combination of Nivolumab With ADG106 in Metastatic NSCLC

Role: collaborator

NCT04111445Phase 1Terminated

Study of ADG116 in Patients With Advanced/Metastatic Solid Tumors

Role: lead

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