Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

7.1%

2 terminated/withdrawn out of 28 trials

Success Rate

92.9%

+6.4% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

31%

8 of 26 completed trials have results

Key Signals

8 with results

Enrollment Performance

Analytics

Phase 1
16(57.1%)
Phase 2
12(42.9%)
28Total
Phase 1(16)
Phase 2(12)

Activity Timeline

Global Presence

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Clinical Trials (28)

Showing 20 of 28 trials
NCT03472885Phase 2Completed

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab

Role: collaborator

NCT00350272Phase 2Completed

Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

Role: collaborator

NCT01180790Phase 2Completed

Safety, Tolerability, and Antiviral Activity of ACH-0141625 or Placebo in Combination With Peginterferon and Ribavirin in Hepatitis C Virus (HCV) Positive Participants

Role: collaborator

NCT01849562Phase 2Completed

Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV Participants

Role: collaborator

NCT01700179Phase 1Completed

Evaluation of Safety, Tolerability, and Antiviral Activity of ACH-0143102 Plus Ribavirin In Treatment-naive Hepatitis C Virus Infection Genotype 1b Participants

Role: collaborator

NCT00312039Phase 1Completed

Study of Once Daily Elvucitabine Versus Lamivudine in Participants With a Documented M184V Mutation

Role: collaborator

NCT00380159Phase 2Completed

Open-Label, 48-Week Extension Study of Elvucitabine in Combination With Background Antiretroviral Therapy (ART) for Participants Who Have Completed Study ACH443-014A

Role: collaborator

NCT00675844Phase 2Completed

An Open-Label Treatment Protocol to Provide Continued Elvucitabine Treatment

Role: collaborator

NCT03181633Phase 2Completed

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Role: collaborator

NCT00401947Phase 2Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection

Role: collaborator

NCT03053102Phase 2Completed

Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Role: collaborator

NCT05109390Phase 1Completed

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Role: collaborator

NCT03124368Phase 2Completed

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Role: collaborator

NCT05047458Phase 1Completed

A Study of Single-dose ALXN2050 in Healthy Adults

Role: collaborator

NCT05047484Phase 1Completed

A Study of Multiple Doses of ALXN2050 in Healthy Adults

Role: collaborator

NCT05016206Phase 1Completed

A Study of the Cardiac Effects of Danicopan in Healthy Adults

Role: collaborator

NCT03384186Phase 1Completed

A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants

Role: collaborator

NCT03555539Phase 1Completed

Study of Danicopan in Participants With Hepatic Impairment

Role: collaborator

NCT04940559Phase 1Completed

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants

Role: collaborator

NCT03108274Phase 1Completed

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Role: collaborator