Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.3%

1 terminated/withdrawn out of 12 trials

Success Rate

91.7%

+5.2% vs industry average

Late-Stage Pipeline

17%

2 trials in Phase 3/4

Results Transparency

27%

3 of 11 completed trials have results

Key Signals

3 with results

Enrollment Performance

Analytics

Phase 1
9(75.0%)
Phase 3
2(16.7%)
Phase 2
1(8.3%)
12Total
Phase 1(9)
Phase 3(2)
Phase 2(1)

Activity Timeline

Global Presence

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Clinical Trials (12)

Showing 12 of 12 trials
NCT01970371Phase 3Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)

Role: lead

NCT02486627Phase 3Completed

A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)

Role: lead

NCT01096849Phase 2Completed

A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP)

Role: lead

NCT03163550Phase 1Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interaction Potential of ACHN-383 and ACHN-789

Role: lead

NCT03270553Phase 1Completed

A Study to Assess the Effect of Plazomicin on the Pharmacokinetics of Metformin

Role: lead

NCT03177278Phase 1Completed

A Study to Assess the Metabolism, Excretion, and Mass Balance of Radio-Labeled Plazomicin

Role: lead

NCT01870245Phase 1Terminated

A Multiple Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers

Role: lead

NCT01597947Phase 1Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers

Role: lead

NCT01462136Phase 1Completed

PK Study of ACHN-490 Injection in Renally Impaired Subjects

Role: lead

NCT01514929Phase 1Completed

A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers

Role: lead

NCT01034774Phase 1Completed

Phase 1 Study to Determine Safety, Blood PK and Lung Penetration

Role: lead

NCT00822978Phase 1Completed

Phase 1 Study for Safety of ACHN-490

Role: lead

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