Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

3.3%

1 terminated/withdrawn out of 30 trials

Success Rate

96.0%

+9.5% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

25%

6 of 24 completed trials have results

Key Signals

6 with results

Enrollment Performance

Analytics

Phase 1
23(76.7%)
Phase 2
6(20.0%)
N/A
1(3.3%)
30Total
Phase 1(23)
Phase 2(6)
N/A(1)

Activity Timeline

Global Presence

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Clinical Trials (30)

Showing 20 of 30 trials
NCT06680479Phase 1Suspended

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Role: collaborator

NCT05781542Phase 1Completed

Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV

Role: collaborator

NCT04177355Phase 1Completed

Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults

Role: collaborator

NCT06267872Phase 1Withdrawn

A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum

Role: collaborator

NCT05983874Phase 1Enrolling By Invitation

A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, Given to a Population of Adults Who Have Received 3 Doses of 300µg BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted

Role: collaborator

NCT04927585Phase 1Completed

Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults

Role: collaborator

NCT03722472Phase 1Completed

Phase 1 Clinical Trial of Single-Vial ID93 + GLA-SE in Healthy Adults

Role: lead

NCT05863585Phase 1Unknown

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Prophylactic HIV Vaccine Candidate

Role: collaborator

NCT04365101Phase 1Unknown

Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19

Role: collaborator

NCT01540474Phase 1Completed

Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive Adults

Role: collaborator

NCT03820414Phase 1Completed

Safety, Tolerability, and Immunogenicity of CRV-101 in Healthy Adult Subjects

Role: collaborator

NCT03799510Phase 2Completed

Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children

Role: collaborator

NCT03806686Phase 2Unknown

Phase 2a Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Healthcare Workers

Role: collaborator

NCT03302897Phase 1Completed

Phase 1 LEP-F1 + GLA-SE Vaccine Trial in Healthy Adult Volunteers

Role: lead

NCT02465216Phase 2Completed

Phase 2a ID93 + GLA-SE Vaccine Trial in TB Patients After Treatment Completion

Role: lead

NCT01927159Phase 1Completed

Phase 1 ID93 + GLA-SE Vaccine Trial in BCG-Vaccinated Healthy Adult Volunteers

Role: lead

NCT03041766Phase 2Completed

Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic Regions

Role: collaborator

NCT01599897Phase 1Completed

Phase 1 ID93 + GLA-SE Vaccine Trial in Healthy Adult Volunteers

Role: lead

NCT02071758Phase 1Completed

Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers

Role: lead

NCT00486382Phase 1Completed

Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India

Role: lead