Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

12.0%

3 terminated/withdrawn out of 25 trials

Success Rate

88.0%

+1.5% vs industry average

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

36%

8 of 22 completed trials have results

Key Signals

8 with results

Enrollment Performance

Analytics

Phase 1
14(56.0%)
Phase 2
10(40.0%)
Phase 3
1(4.0%)
25Total
Phase 1(14)
Phase 2(10)
Phase 3(1)

Activity Timeline

Global Presence

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Clinical Trials (25)

Showing 20 of 25 trials
NCT02553317Phase 3Completed

Phase III Trial With Caplacizumab in Patients With Acquired Thrombotic Thrombocytopenic Purpura

Role: lead

NCT01020383Phase 2Completed

Comparative Study of ALX-0081 Versus GPIIb/IIIa Inhibitor in High Risk Percutaneous Coronary Intervention (PCI) Patients

Role: lead

NCT01151423Phase 2Completed

Study to Assess Efficacy and Safety of Anti-von Willebrand Factor (vWF) Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Role: lead

NCT02979431Phase 2Completed

Dose Ranging Study of ALX-0171 in Infants Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection

Role: lead

NCT02309359Phase 2Completed

A Dose-Range Finding Study for ALX-0061 Combination Therapy in Subjects With Rheumatoid Arthritis

Role: lead

NCT02287922Phase 2Completed

A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis

Role: lead

NCT03418571Phase 2Terminated

Evaluation of ALX-0171 in Japanese Children Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection

Role: lead

NCT02518620Phase 2Completed

An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis

Role: lead

NCT03468829Phase 2Withdrawn

Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection

Role: lead

NCT02437890Phase 2Completed

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

Role: lead

NCT02309320Phase 1Completed

A Multicentre Study in Otherwise Healthy Infants and Toddlers Hospitalised For and Diagnosed With RSV Lower Respiratory Tract Infection to Evaluate the Safety, Tolerability, and Clinical Activity of ALX-0171

Role: lead

NCT02101073Phase 1Completed

ALX-0061 Phase I Bioavailability Study in Healthy Volunteers

Role: lead

NCT01284569Phase 1Completed

Study to Assess Safety and Efficacy of Anti-Interleukin 6-receptor (IL6R) Nanobody in Rheumatoid Arthritis (RA) Patients

Role: lead

NCT01483911Phase 1Completed

ALX-0171 Phase I Study, Evaluating Single Ascending Dose and Multiple Dose in Healthy Male Volunteers

Role: lead

NCT01875926Phase 1Completed

ALX-0171 Phase I Pharmacokinetic Study in Healthy Male Volunteers

Role: lead

NCT01909843Phase 1Completed

ALX-0171 Safety Study in Adults With Hyperresponsive Airways

Role: lead

NCT03172208Phase 1Completed

Caplacizumab Single and Multiple Dose Study in Healthy Japanese and White Subjects.

Role: lead

NCT01063803Phase 2Completed

Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis

Role: lead

NCT02189733Phase 1Completed

Bioequivalence of Liquid and Reconstituted Lyophilized Subcutaneous Formulations of Caplacizumab.

Role: lead

NCT01007175Phase 1Completed

Study Evaluating Multiple Ascending Doses Of ATN-103 In Japanese Subjects With Rheumatoid Arthritis

Role: lead