Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.7%

2 terminated/withdrawn out of 23 trials

Success Rate

88.9%

+2.4% vs industry average

Late-Stage Pipeline

13%

3 trials in Phase 3/4

Results Transparency

50%

8 of 16 completed trials have results

Key Signals

2 recruiting8 with results

Enrollment Performance

Analytics

Phase 2
13(56.5%)
Phase 1
7(30.4%)
Phase 3
3(13.0%)
23Total
Phase 2(13)
Phase 1(7)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (23)

Showing 20 of 23 trials
NCT04023396Phase 2Completed

Efficacy and Safety Study of ABX464 as Maintenance Therapy in Patients With Moderate to Severe Ulcerative Colitis

Role: lead

NCT06456593Phase 2Recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Role: lead

NCT05177835Phase 2Active Not Recruiting

Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis

Role: lead

NCT07453784Phase 1Not Yet Recruiting

Phase 1 Study to Evaluate Pharmacokinetics, Relative Bioavailability, Palatability of Obefazimod Minitablet Formulation

Role: lead

NCT03760003Phase 2Completed

Dose-Ranging Phase 2b Study of ABX464 in Moderate to Severe Ulcerative Colitis

Role: lead

NCT04393038Phase 2Terminated

ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19

Role: lead

NCT04049448Phase 2Completed

Study Evaluating the Long-Term Safety and Efficacy of ABX464 in Patients With Moderate to Severe Rheumatoid Arthritis

Role: lead

NCT05535946Phase 3Active Not Recruiting

ABTECT - Maintenance

Role: lead

NCT05507216Phase 3Completed

ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

Role: lead

NCT05507203Phase 3Completed

ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Role: lead

NCT03368118Phase 2Completed

Study Evaluating the Long-term Safety and Efficacy of ABX464 in Active Ulcerative Colitis

Role: lead

NCT02735863Phase 2Completed

ABX464 in Fully Controlled HIV Infected Patients Treated With Boosted Protease Inhibitor Treatment

Role: lead

NCT03905109Phase 2Withdrawn

Phase 2b/3 Study of ABX464 in Moderate to Severe Active Crohn's Disease Patients

Role: lead

NCT03093259Phase 2Completed

ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis

Role: lead

NCT02792686Phase 1Completed

ABX464 First in Man Study

Role: lead

NCT02990325Phase 1Completed

A Safety, Pharmacokinetics, and Pharmacodynamics Study of ABX464 in HIV-1 Seronegative and Seropositive Adults

Role: lead

NCT03813199Phase 2Completed

Study of Two Doses of ABX464 in Participants With Moderate to Severe Rheumatoid Arthritis

Role: lead

NCT05032560Phase 1Completed

Safety and Pharmacokinetics Study in Healthy Japanese Volunteers

Role: lead

NCT05121714Phase 1Completed

Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464

Role: lead

NCT03897543Phase 1Recruiting

ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma

Role: lead