Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
11(69%)
Results Posted
67%(2 trials)

Phase Distribution

Ph phase_3
4
25%
Ph not_applicable
1
6%
Ph phase_1
3
19%
Ph phase_2
6
38%

Phase Distribution

3

Early Stage

6

Mid Stage

4

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
3(21.4%)
Phase 2Efficacy & side effects
6(42.9%)
Phase 3Large-scale testing
4(28.6%)
N/ANon-phased studies
1(7.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

3 of 3 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

11

trials recruiting

Total Trials

16

all time

Status Distribution
Active(12)
Completed(3)
Other(1)

Detailed Status

Recruiting6
Active, not recruiting5
Completed3
Not yet recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
11
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (21.4%)
Phase 26 (42.9%)
Phase 34 (28.6%)
N/A1 (7.1%)

Trials by Status

not_yet_recruiting16%
recruiting638%
unknown16%
completed319%
active_not_recruiting531%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT03504397Phase 3

A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer.

Active Not Recruiting
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting
NCT03653507Phase 3

A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

Active Not Recruiting
NCT07431281Phase 3

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Recruiting
NCT03816163Phase 2

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

Active Not Recruiting
NCT06902545

A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer.

Recruiting
NCT06468280Phase 2

Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer

Recruiting
NCT06962137Phase 2

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Recruiting
NCT06396091Phase 1

A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer

Active Not Recruiting
NCT03505320Phase 2

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Active Not Recruiting
NCT06048081

Early Access Program for Zolbetuximab

Unknown
NCT06732856Phase 1

A Phase Ib/II Trial of Neoadjuvant Zolbetuximab Plus Docetaxel, Oxaliplatin and S-1 Chemotherapy in Patients With Locally Advanced Gastric Cancer

Recruiting
NCT01630083Phase 2

Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer

Completed
NCT06881017Phase 2

Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular Subtyping

Not Yet Recruiting
NCT03528629Not Applicable

A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Completed
NCT04086758Phase 1

A Pharmacokinetic Study of Zolbetuximab (IMAB362) in Chinese Subjects With Locally Advanced Unresectable or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Completed

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16