Success Metrics

Clinical Success Rate
76.9%

Based on 10 completed trials

Completion Rate
77%(10/13)
Active Trials
32(62%)
Results Posted
30%(3 trials)
Terminated
3(6%)

Phase Distribution

Ph phase_3
4
8%
Ph phase_2
25
48%
Ph phase_1
22
42%
Ph early_phase_1
1
2%

Phase Distribution

23

Early Stage

25

Mid Stage

4

Late Stage

Phase Distribution52 total trials
Early Phase 1First-in-human
1(1.9%)
Phase 1Safety & dosage
22(42.3%)
Phase 2Efficacy & side effects
25(48.1%)
Phase 3Large-scale testing
4(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

10 of 15 finished

Non-Completion Rate

33.3%

5 ended early

Currently Active

32

trials recruiting

Total Trials

52

all time

Status Distribution
Active(34)
Completed(10)
Terminated(5)
Other(3)

Detailed Status

Active, not recruiting19
Recruiting13
Completed10
Terminated3
unknown2
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
52
Active
32
Success Rate
76.9%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.9%)
Phase 122 (42.3%)
Phase 225 (48.1%)
Phase 34 (7.7%)

Trials by Status

active_not_recruiting1937%
recruiting1325%
unknown24%
completed1019%
suspended12%
not_yet_recruiting24%
withdrawn24%
terminated36%

Recent Activity

Clinical Trials (52)

Showing 20 of 52 trialsScroll for more
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT05007782Phase 1

Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

Active Not Recruiting
NCT04104672Phase 1

A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies

Completed
NCT06727565Phase 2

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

Active Not Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Completed
NCT03547973Phase 2

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Active Not Recruiting
NCT04736173Phase 2

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Active Not Recruiting
NCT05536141Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Recruiting
NCT07619313Phase 1

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

Recruiting
NCT06048133Phase 2

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

Active Not Recruiting
NCT05335941Phase 2

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Active Not Recruiting
NCT06759649Phase 1

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Recruiting
NCT05840224Phase 1

Study of GS-4528 in Adults With Solid Tumors

Active Not Recruiting
NCT07710885Phase 3

Futibatinib (TAS-120) in Patients With Advanced Biliary Tract Cancer

Recruiting
NCT05724563Phase 2

Domvanalimab and Zimberelimab in Advanced Liver Cancers

Active Not Recruiting
NCT04262856Phase 2

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Completed
NCT04791839Phase 2

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05419479Phase 1

Switch Maintenance in Pancreatic

Suspended
NCT05676931Phase 2

Study With Various Immunotherapy Treatments in Participants With Lung Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
52