Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
32(64%)
Results Posted
38%(3 trials)
Terminated
3(6%)

Phase Distribution

Ph phase_2
25
50%
Ph early_phase_1
1
2%
Ph phase_3
3
6%
Ph phase_1
21
42%

Phase Distribution

22

Early Stage

25

Mid Stage

3

Late Stage

Phase Distribution50 total trials
Early Phase 1First-in-human
1(2.0%)
Phase 1Safety & dosage
21(42.0%)
Phase 2Efficacy & side effects
25(50.0%)
Phase 3Large-scale testing
3(6.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.5%

8 of 13 finished

Non-Completion Rate

38.5%

5 ended early

Currently Active

32

trials recruiting

Total Trials

50

all time

Status Distribution
Active(34)
Completed(8)
Terminated(5)
Other(3)

Detailed Status

Active, not recruiting18
Recruiting14
Completed8
Terminated3
unknown2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
50
Active
32
Success Rate
72.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.0%)
Phase 121 (42.0%)
Phase 225 (50.0%)
Phase 33 (6.0%)

Trials by Status

completed816%
terminated36%
unknown24%
active_not_recruiting1836%
withdrawn24%
recruiting1428%
not_yet_recruiting24%
suspended12%

Recent Activity

Clinical Trials (50)

Showing 20 of 50 trialsScroll for more
NCT04791839Phase 2

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05536141Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Recruiting
NCT04736173Phase 2

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Active Not Recruiting
NCT06431633Phase 3

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.

Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT06532565Phase 1

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

Recruiting
NCT04656535Early Phase 1

AB154 Combined With AB122 for Recurrent Glioblastoma

Active Not Recruiting
NCT06082960Phase 1

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Active Not Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT05130177Phase 2

Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma

Active Not Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT04104672Phase 1

A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies

Active Not Recruiting
NCT07397611Phase 2

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

Recruiting
NCT03547973Phase 2

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Recruiting
NCT06133517Phase 2

PeRioperative Immunotherapy Combined With Sacituzumab Govitecan in Muscle Invasive blAdder Cancer

Active Not Recruiting
NCT05824468Phase 2

Zimberelimab Plus Lenvatinib After Progression on Prior Immune Checkpoint Inhibitors for Advanced Cervical Cancer

Active Not Recruiting
NCT05335941Phase 2

A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Active Not Recruiting
NCT06727565Phase 2

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

Active Not Recruiting
NCT06759649Phase 1

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Recruiting
NCT06048484Phase 2

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
50