Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
33(63%)
Results Posted
38%(3 trials)
Terminated
3(6%)

Phase Distribution

Ph phase_2
25
48%
Ph phase_3
4
8%
Ph early_phase_1
1
2%
Ph phase_1
22
42%

Phase Distribution

23

Early Stage

25

Mid Stage

4

Late Stage

Phase Distribution52 total trials
Early Phase 1First-in-human
1(1.9%)
Phase 1Safety & dosage
22(42.3%)
Phase 2Efficacy & side effects
25(48.1%)
Phase 3Large-scale testing
4(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

61.5%

8 of 13 finished

Non-Completion Rate

38.5%

5 ended early

Currently Active

33

trials recruiting

Total Trials

52

all time

Status Distribution
Active(36)
Completed(8)
Terminated(5)
Other(3)

Detailed Status

Active, not recruiting19
Recruiting14
Completed8
Not yet recruiting3
Terminated3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
52
Active
33
Success Rate
72.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.9%)
Phase 122 (42.3%)
Phase 225 (48.1%)
Phase 34 (7.7%)

Trials by Status

not_yet_recruiting36%
terminated36%
suspended12%
completed815%
active_not_recruiting1937%
recruiting1427%
unknown24%
withdrawn24%

Recent Activity

Clinical Trials (52)

Showing 20 of 52 trialsScroll for more
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT04736173Phase 2

Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer

Active Not Recruiting
NCT05536141Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Recruiting
NCT05840224Phase 1

Study of GS-4528 in Adults With Solid Tumors

Active Not Recruiting
NCT07710885Phase 3

Futibatinib (TAS-120) in Patients With Advanced Biliary Tract Cancer

Recruiting
NCT06048133Phase 2

Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)

Active Not Recruiting
NCT05724563Phase 2

Domvanalimab and Zimberelimab in Advanced Liver Cancers

Active Not Recruiting
NCT04104672Phase 1

A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies

Active Not Recruiting
NCT04262856Phase 2

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Completed
NCT04791839Phase 2

Safety and Efficacy of Zimberelimab (AB122) in Combination With Domvanalimab (AB154) and Etrumadenant (AB928) in Patients With Previously Treated Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05419479Phase 1

Switch Maintenance in Pancreatic

Suspended
NCT07619313Phase 1

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

Not Yet Recruiting
NCT05676931Phase 2

Study With Various Immunotherapy Treatments in Participants With Lung Cancer

Active Not Recruiting
NCT05688215Phase 1

Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Recruiting
NCT06431633Phase 3

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.

Recruiting
NCT06532565Phase 1

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

Recruiting
NCT04656535Early Phase 1

AB154 Combined With AB122 for Recurrent Glioblastoma

Active Not Recruiting
NCT06082960Phase 1

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
52