Success Metrics

Clinical Success Rate
75.0%

Based on 12 completed trials

Completion Rate
75%(12/16)
Active Trials
0(0%)
Results Posted
50%(6 trials)
Terminated
4(25%)

Phase Distribution

Ph phase_1
6
38%
Ph phase_2
10
63%

Phase Distribution

6

Early Stage

10

Mid Stage

0

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
6(37.5%)
Phase 2Efficacy & side effects
10(62.5%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

75.0%

12 of 16 finished

Non-Completion Rate

25.0%

4 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Completed(12)
Terminated(4)

Detailed Status

Completed12
Terminated4

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
75.0%
Most Advanced
Phase 2

Trials by Phase

Phase 16 (37.5%)
Phase 210 (62.5%)

Trials by Status

terminated425%
completed1275%

Recent Activity

Clinical Trials (16)

Showing 16 of 16 trials
NCT00613626Phase 2

Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer

Completed
NCT00272350Phase 1

ZD6474 to Treat Advanced Brain Cancer in Patients

Completed
NCT00441142Phase 1

Zactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain Tumors

Completed
NCT00807170Phase 1

Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases

Terminated
NCT00047840Phase 2

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.

Completed
NCT00071188Phase 2

ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Completed
NCT00034918Phase 2

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer

Completed
NCT00059722Phase 2

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

Completed
NCT00047788Phase 2

Efficacy Study of ZD6474 to Treat Multiple Myeloma Cancer

Completed
NCT00290537Phase 2

Phase II Study of ZD6474 in Advanced NSCLC

Terminated
NCT00402896Phase 2

Malignant Pleural Effusion With ZD6474

Terminated
NCT00410189Phase 2

BATTLE Program: ZD6474 in Previously Treated Subjects With NSCLC

Completed
NCT00551096Phase 1

Gemcitabine/Capecitabine/ZD6474 in Advanced Solid Tumors

Completed
NCT00459043Phase 2

Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and Neck

Completed
NCT00436072Phase 1

ZD6474, Cetuximab, and Irinotecan in Patients With Metastatic Colorectal Cancer

Completed
NCT00533169Phase 1

ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma

Terminated

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16