Success Metrics

Completion Rate
0%(0/1)
Active Trials
25(66%)
Terminated
1(3%)

Phase Distribution

Ph phase_1
11
29%
Ph phase_2
23
61%
Ph phase_3
4
11%

Phase Distribution

11

Early Stage

23

Mid Stage

4

Late Stage

Phase Distribution38 total trials
Phase 1Safety & dosage
11(28.9%)
Phase 2Efficacy & side effects
23(60.5%)
Phase 3Large-scale testing
4(10.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 1 finished

Non-Completion Rate

100.0%

1 ended early

Currently Active

25

trials recruiting

Total Trials

38

all time

Status Distribution
Active(37)
Terminated(1)

Detailed Status

Recruiting24
Not yet recruiting12
Terminated1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
38
Active
25
Success Rate
0.0%
Most Advanced
Phase 3

Trials by Phase

Phase 111 (28.9%)
Phase 223 (60.5%)
Phase 34 (10.5%)

Trials by Status

terminated13%
recruiting2463%
active_not_recruiting13%
not_yet_recruiting1232%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT07489495Phase 3

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

Recruiting
NCT07527169Phase 2

A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory Neuroblastoma

Not Yet Recruiting
NCT06943755Phase 2

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Recruiting
NCT07750158Phase 3

Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

Not Yet Recruiting
NCT05176483Phase 1

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

Recruiting
NCT07227402Phase 3

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Recruiting
NCT07470489Phase 2

Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer

Not Yet Recruiting
NCT06959511Phase 2

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Recruiting
NCT07043608Phase 2

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

Recruiting
NCT07428616Phase 2

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

Recruiting
NCT07714551Phase 2

Zanzalintinib in Unresectable and Progressive MPGGs

Not Yet Recruiting
NCT07218666Phase 2

Zanzalintinib in Men With Aggressive Variant Prostate Cancer

Recruiting
NCT07049926Phase 1

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Recruiting
NCT07682675Phase 2

Study to Evaluate the Efficacy of Zanzalintinib in the Treatment of Relapsed or Metastatic Adenoid Cystic Carcinomas of the Head and Neck

Not Yet Recruiting
NCT07677579Phase 2

NIMBLE-CRC: NeoImmunoModulation Before Leveraging Excision in Colorectal Rectal Cancer

Not Yet Recruiting
NCT06968988Phase 1

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Recruiting
NCT06959641Phase 2

XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

Recruiting
NCT07042919Phase 1

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Recruiting
NCT07193550Phase 2

A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)

Recruiting
NCT06952010Phase 1

A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
38