Success Metrics

Completion Rate
0%(0/1)
Active Trials
20(69%)
Terminated
1(3%)

Phase Distribution

Ph phase_1
10
34%
Ph phase_2
17
59%
Ph phase_3
2
7%

Phase Distribution

10

Early Stage

17

Mid Stage

2

Late Stage

Phase Distribution29 total trials
Phase 1Safety & dosage
10(34.5%)
Phase 2Efficacy & side effects
17(58.6%)
Phase 3Large-scale testing
2(6.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 1 finished

Non-Completion Rate

100.0%

1 ended early

Currently Active

20

trials recruiting

Total Trials

29

all time

Status Distribution
Active(28)
Terminated(1)

Detailed Status

Recruiting19
Not yet recruiting8
Terminated1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
29
Active
20
Success Rate
0.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (34.5%)
Phase 217 (58.6%)
Phase 32 (6.9%)

Trials by Status

terminated13%
recruiting1966%
active_not_recruiting13%
not_yet_recruiting828%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT07226063Phase 2

Maintenance Zanzalintinib and Durvalumab in Participants With Advanced Hepatocellular Cancer

Not Yet Recruiting
NCT07227402Phase 3

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Recruiting
NCT07489495Phase 3

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

Recruiting
NCT07043608Phase 2

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

Not Yet Recruiting
NCT06959511Phase 2

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Recruiting
NCT06943755Phase 2

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Recruiting
NCT07283731Phase 2

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

Recruiting
NCT07470489Phase 2

Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer

Not Yet Recruiting
NCT07527169Phase 2

A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory Neuroblastoma

Not Yet Recruiting
NCT07049926Phase 1

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Recruiting
NCT05176483Phase 1

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Recruiting
NCT07193550Phase 2

A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)

Recruiting
NCT07428616Phase 2

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

Not Yet Recruiting
NCT06571734Phase 2

XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma

Recruiting
NCT06968988Phase 1

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Recruiting
NCT07185945Phase 2

Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior Therapy

Not Yet Recruiting
NCT06926634Phase 2

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

Recruiting
NCT06795009Phase 1

Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Recruiting
NCT06912087Phase 1

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

Recruiting
NCT06937866Phase 1

Maintenance Zanzalintinib With Etoposide After HDCT in GCT

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
29